| Compound ID |
Compound Name |
Compound Formula |
|
CP0494834
|
3-[2-(1-Oxa-2-aza-spiro[4.5]dec-2-en-3-yl)-6-(2-trifluoromethylphenyl)-3H-benzimidazol-4-yl]-propan-1-ol
Show/Hide
|
C25H26F3N3O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0481801
|
4-[[3-fluoro-4-(trifluoromethyl)phenyl]methyl-(3-methyl-1-benzothiophen-2-yl)sulfamoyl]benzoic acid
Show/Hide
|
C24H17F4NO4S2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0529492
|
US9409915, 89
Show/Hide
|
C22H20Cl2F3N5O
|
1
|
| 1 |
IC50 = 0.53 nM
|
|
|
|
CP0493185
|
US9409915, 16
Show/Hide
|
C24H25ClF3N5O
|
1
|
| 1 |
IC50 = 0.59 nM
|
|
|
|
CP0523411
|
3-[5-(2-Fluoro-6-trifluoromethylphenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H19F4N3O
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0518513
|
US9434711, 489
Show/Hide
|
C23H17ClFNO4S2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0554395
|
US9434711, 227
Show/Hide
|
C21H21F4NO3S2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0529489
|
US9409915, 21
Show/Hide
|
C25H25F3N6O2
|
1
|
| 1 |
IC50 = 0.69 nM
|
|
|
|
CP0499104
|
2-(1-Oxa-2-aza-spiro[4.5]dec-2-en-3-yl)-6-(2-trifluoromethylphenyl)-3H-benzimidazole-4-carbonitrile
Show/Hide
|
C23H19F3N4O
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0451469
|
US9434711, 808
Show/Hide
|
C24H17F3N4O5S2
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0531709
|
US9434711, 518
Show/Hide
|
C24H18F3NO4S2
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0486331
|
US9409915, 90
Show/Hide
|
C23H20ClF6N5O2
|
1
|
| 1 |
IC50 = 0.73 nM
|
|
|
|
CP0231446
|
3-[7-Trifluoromethyl-5-(2-trifluoromethyl-phenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C23H19F6N3O
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0503609
|
3-[5-(2-Fluoro-6-trifluoromethoxyphenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H19F4N3O2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0067499
|
4-[[4-fluoro-3-(trifluoromethyl)phenyl]methyl-(3-methyl-1-benzothiophen-2-yl)sulfamoyl]benzoic acid
Show/Hide
|
C24H17F4NO4S2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0474915
|
US9434711, 361
Show/Hide
|
C26H21F4NO5S2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0495347
|
US9434711, 496
Show/Hide
|
C24H18F3NO5S2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0537408
|
US9434711, 292
Show/Hide
|
C23H14BrF4NO4S2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0561962
|
US9434711, 493
Show/Hide
|
C23H14F5NO4S2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0493186
|
US9409915, 19
Show/Hide
|
C23H20ClF6N5O
|
1
|
| 1 |
IC50 = 0.84 nM
|
|
|
|
CP0379735
|
8,8-Difluoro-3-[5-(2-trifluoromethylphenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H18F5N3O
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0400378
|
US9434711, 249
Show/Hide
|
C25H26BrNO2S2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0495366
|
US9434711, 755
Show/Hide
|
C26H20F3NO5S2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0515446
|
US9434711, 494
Show/Hide
|
C24H18F3NO6S3
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0465865
|
US9409915, 20
Show/Hide
|
C24H25ClF3N5O2
|
1
|
| 1 |
IC50 = 0.95 nM
|
|
|
|
CP0523412
|
3-[5-(2-Chlorophenyl)-7-trifluoromethyl-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H19ClF3N3O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0444956
|
US9434711, 491
Show/Hide
|
C24H18F3NO4S2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0474910
|
US9434711, 335
Show/Hide
|
C25H19F4NO5S2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0482843
|
US9434711, 224
Show/Hide
|
C19H17F4NO3S2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0495345
|
US9434711, 488
Show/Hide
|
C23H17F2NO4S2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0495346
|
US9434711, 490
Show/Hide
|
C24H19F2NO5S2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0495350
|
US9434711, 526
Show/Hide
|
C24H18F3NO4S3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0559291
|
US9434711, 810
Show/Hide
|
C25H18F3N3O4S3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0561211
|
US9434711, 278
Show/Hide
|
C26H26BrNO4S2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0561964
|
US9434711, 535
Show/Hide
|
C20H19F4NO3S2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0567902
|
US9434711, 218
Show/Hide
|
C24H17F4NO5S2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0549577
|
3-[5-(2-Trifluoromethoxyphenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H20F3N3O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0539958
|
US9409915, 59
Show/Hide
|
C25H26ClF3N6O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0373618
|
3-[5-(2-Trifluoromethoxyphenyl)-7-trifluoromethyl-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C23H19F6N3O2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0548920
|
US9409915, 93
Show/Hide
|
C24H25ClF3N5O2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0568268
|
US9409915, 14
Show/Hide
|
C25H25F3N6O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0482841
|
US9434711, 220
Show/Hide
|
C20H19F4NO3S2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0495370
|
US9434711, 774
Show/Hide
|
C24H17F4NO5S2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0561212
|
US9434711, 279
Show/Hide
|
C22H22BrNO4S2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0517152
|
3-[7-Trifluoromethyl-5-(2-trifluoromethylphenyl)-1H-benzimidazol-2-yl]-1,8-dioxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H17F6N3O2
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0516722
|
US9409915, 22
Show/Hide
|
C27H28F3N7
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0419265
|
US9434711, 756
Show/Hide
|
C27H22F3NO5S2
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0537404
|
US9434711, 213
Show/Hide
|
C22H17F2NO3S2
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0489681
|
US9409915, 57
Show/Hide
|
C23H23ClF3N5O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0419268
|
US9434711, 775
Show/Hide
|
C24H16F5NO4S2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0502137
|
3-[5-(2-Fluorophenyl)-7-trifluoromethyl-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H19F4N3O
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0577859
|
US9409915, 17
Show/Hide
|
C22H21ClN6O
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0482842
|
US9434711, 222
Show/Hide
|
C23H19F2NO3S2
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0556911
|
US9067935, 3
Show/Hide
|
C21H15ClF3N3O3S
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0526155
|
US9409915, 83
Show/Hide
|
C23H23ClN6O2
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0568269
|
US9409915, 15
Show/Hide
|
C24H20F6N6O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0444986
|
US9434711, 566
Show/Hide
|
C26H21F4NO4S2
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0493401
|
US9434711, 544
Show/Hide
|
C25H17F4N3O4S2
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0517097
|
US9434711, 294
Show/Hide
|
C23H14ClF4NO4S2
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0520873
|
US9434711, 592
Show/Hide
|
C24H16F5NO4S2
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0379790
|
US9409915, 84
Show/Hide
|
C24H23F3N6O2
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0493402
|
US9434711, 545
Show/Hide
|
C21H20F3NO4S2
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0419248
|
US9067935, 75
Show/Hide
|
C24H16BrF4N5O2S
|
1
|
| 1 |
IC50 = 1.94 nM
|
|
|
|
CP0507303
|
US9409915, 58
Show/Hide
|
C22H23Cl2N5O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0419262
|
US9434711, 711
Show/Hide
|
C23H13BrF5NO4S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0444983
|
US9434711, 534
Show/Hide
|
C20H19F4NO3S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0451429
|
US9434711, 439
Show/Hide
|
C23H22BrNO4S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0474907
|
US9434711, 296
Show/Hide
|
C23H15F4NO4S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0480808
|
US9434711, 226
Show/Hide
|
C20H21F2NO3S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0492927
|
US9434711, 487
Show/Hide
|
C23H18FNO4S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0495348
|
US9434711, 517
Show/Hide
|
C23H16F3NO4S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0495349
|
US9434711, 521
Show/Hide
|
C23H17ClFNO4S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0512618
|
US9434711, 524
Show/Hide
|
C24H17F2NO6S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0529037
|
US9434711, 475
Show/Hide
|
C23H14BrF4N5O2S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0531491
|
US9434711, 453
Show/Hide
|
C23H24BrNO5S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0537429
|
US9434711, 140
Show/Hide
|
C21H15BrFNO2S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0554374
|
US9434711, 68
Show/Hide
|
C26H22F4N2O3S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0554985
|
US9434711, 438
Show/Hide
|
C21H20BrNO4S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0564117
|
US9434711, 698
Show/Hide
|
C27H21F4NO4S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0565749
|
US9434711, 523
Show/Hide
|
C24H19NO6S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0554385
|
US9434711, 148
Show/Hide
|
C21H14BrF2NO2S2
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0563143
|
US9434711, 214
Show/Hide
|
C23H17F4NO3S2
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0373616
|
3-[7-Fluoro-5-(2-trifluoromethylphenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H19F4N3O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0516735
|
US9434711, 785
Show/Hide
|
C24H18F3N5O3S2
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0531721
|
US9434711, 805
Show/Hide
|
C23H17F3N6O3S2
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0566236
|
US9067935, 77
Show/Hide
|
C24H17BrF3N5O3S
|
1
|
| 1 |
IC50 = 2.27 nM
|
|
|
|
CP0499103
|
3-[5-(2,6-Difluorophenyl)-1H-benzimidazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene
Show/Hide
|
C21H19F2N3O
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0406616
|
US9434711, 542
Show/Hide
|
C24H17F4N5O2S2
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0537405
|
US9434711, 223
Show/Hide
|
C24H19F4NO3S2
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0914674
|
US9067935, 109
Show/Hide
|
C25H22F3N3O5S
|
1
|
| 1 |
IC50 = 2.31 nM
|
|
|
|
CP0502136
|
3-[5-(2-Chlorophenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro-[4.5]dec-2-ene
Show/Hide
|
C21H20ClN3O
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0519193
|
US9434711, 675
Show/Hide
|
C26H19F4NO4S2
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0561965
|
US9434711, 568
Show/Hide
|
C23H24F3NO4S2
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0523410
|
3-[5-(2-Difluoromethoxyphenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H21F2N3O2
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0444951
|
US9434711, 285
Show/Hide
|
C22H17F2NO3S2
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0531521
|
US9434711, 174
Show/Hide
|
C22H15BrF3NO3S2
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0482838
|
US9434711, 152
Show/Hide
|
C17H14BrF2NO2S2
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0523652
|
3-[7-Bromo-5-(2-trifluoromethylphenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H19BrF3N3O
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0402744
|
US9409915, 92
Show/Hide
|
C23H25ClFN5O
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0518524
|
US9434711, 801
Show/Hide
|
C25H18F3N3O5S2
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0529418
|
US9434711, 129
Show/Hide
|
C20H15F2NO2S3
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0537398
|
US9434711, 176
Show/Hide
|
C22H17BrFNO3S2
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0472436
|
3-[5-(2-Fluorophenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro-[4.5]dec-2-ene
Show/Hide
|
C21H20FN3O
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0553265
|
2-(1-benzothiophen-2-yl)-2-(2-fluoroanilino)-1-[(2S)-2-(2-fluorophenyl)pyrrolidin-1-yl]ethanone
Show/Hide
|
C26H22F2N2OS
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0400368
|
US9434711, 69
Show/Hide
|
C25H17F4N3O2S3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0507269
|
US9434711, 395
Show/Hide
|
C20H17BrF3NO4S2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0512617
|
US9434711, 511
Show/Hide
|
C24H14BrF4N3O4S2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0516764
|
US9434711, 781
Show/Hide
|
C26H22F3NO6S2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0517089
|
US9434711, 205
Show/Hide
|
C20H17F4NO3S2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0531476
|
US9434711, 275
Show/Hide
|
C21H22BrNO5S2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0537425
|
US9434711, 38
Show/Hide
|
C21H15F4NO2S3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0554366
|
US9434711, 13
Show/Hide
|
C22H17F3N2O3S2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0564448
|
US9434711, 707
Show/Hide
|
C20H16BrF4NO4S2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0567901
|
US9434711, 217
Show/Hide
|
C19H17F4NO3S2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0572306
|
US9434711, 299
Show/Hide
|
C24H15F4NO5S2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0335008
|
3-[5-(2-Trifluoromethyl-phenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H20F3N3O
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0486325
|
US9409915, 63
Show/Hide
|
C26H28ClF3N6
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0560158
|
US9067935, 79
Show/Hide
|
C24H16BrF4N5O2S
|
1
|
| 1 |
IC50 = 3.17 nM
|
|
|
|
CP0556987
|
US9067935, 53
Show/Hide
|
C24H22F3N3O2S
|
1
|
| 1 |
IC50 = 3.19 nM
|
|
|
|
CP0495547
|
US9409915, 65
Show/Hide
|
C26H26F3N7O
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0419246
|
US9434711, 559
Show/Hide
|
C22H25BrN2O3S2
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0556983
|
US9067935, 1
Show/Hide
|
C21H14ClF4N3O2S
|
1
|
| 1 |
IC50 = 3.25 nM
|
|
|
|
CP0478520
|
3-[7-Chloro-5-(2-trifluoromethylphenyl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H19ClF3N3O
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0530435
|
US9434711, 784
Show/Hide
|
C25H17F4N3O3S3
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0559645
|
US9067935, 25
Show/Hide
|
C21H14BrF4N3O2S
|
1
|
| 1 |
IC50 = 3.49 nM
|
|
|
|
CP0517254
|
US9409915, 11
Show/Hide
|
C21H21Cl2N5O
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0495816
|
Piperidine-1-sulfonic acid (3-methyl-benzo[b]thiophen-2-yl)-(4-trifluoromethoxy-benzyl)-amide
Show/Hide
|
C23H25F3N2O3S2
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0531523
|
US9434711, 179
Show/Hide
|
C22H18BrNO2S2
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0451421
|
US9434711, 165
Show/Hide
|
C22H17Br2NO3S2
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0465971
|
US9434711, 811
Show/Hide
|
C22H21F3N4O3S2
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0554391
|
US9434711, 186
Show/Hide
|
C20H12BrF4NO2S3
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0490243
|
US9409915, 91
Show/Hide
|
C22H20ClF4N5O
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0445004
|
US9434711, 39
Show/Hide
|
C22H16F4N2O2S2
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0531525
|
US9434711, 184
Show/Hide
|
C20H12BrF4NO2S3
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0564114
|
US9434711, 587
Show/Hide
|
C17H14BrF3N2O2S2
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0572470
|
US9434711, 799
Show/Hide
|
C25H23F3N2O3S2
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0502084
|
3-[7-Chloro-5-(2-trifluoromethyl-phenyl)-1H-benzimidazol-2-yl]-1,8-dioxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C21H17ClF3N3O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0423918
|
US9434711, 155
Show/Hide
|
C21H13BrF3NO2S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0426354
|
US9434711, 4
Show/Hide
|
C21H15ClFNO2S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0451438
|
US9434711, 712
Show/Hide
|
C21H17BrF3N3O3S3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0474773
|
US9434711, 436
Show/Hide
|
C21H23NO7S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0474901
|
US9434711, 225
Show/Hide
|
C18H17F2NO3S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0480828
|
US9434711, 454
Show/Hide
|
C21H22BrNO5S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0497602
|
US9434711, 522
Show/Hide
|
C24H17F4NO4S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0515445
|
US9434711, 486
Show/Hide
|
C23H19NO4S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0531485
|
US9434711, 374
Show/Hide
|
C26H23F4NO3S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0532614
|
US9434711, 650
Show/Hide
|
C22H15BrF4N2O2S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0554373
|
US9434711, 66
Show/Hide
|
C24H16F4N2O4S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0554379
|
US9434711, 96
Show/Hide
|
C22H26N2O2S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0559277
|
US9434711, 512
Show/Hide
|
C24H14ClF4N3O4S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0881238
|
US9067935, 122
Show/Hide
|
C23H17F4N3O5S
|
1
|
| 1 |
IC50 = 4.03 nM
|
|
|
|
CP0560968
|
US9067935, 98
Show/Hide
|
C24H17ClF3N5O2S
|
1
|
| 1 |
IC50 = 4.04 nM
|
|
|
|
CP0559295
|
US9434711, 838
Show/Hide
|
C21H24FNO4S2
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0414510
|
US9409915, 54
Show/Hide
|
C26H30Cl2N6O2
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0444987
|
US9434711, 591
Show/Hide
|
C21H19F4NO4S2
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0561967
|
US9434711, 589
Show/Hide
|
C21H20FNO4S2
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0564449
|
US9434711, 721
Show/Hide
|
C22H20F3N3O2S2
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0561974
|
US9434711, 658
Show/Hide
|
C23H24F3NO5S2
|
1
|
| 1 |
IC50 = 4.3 nM
|
|
|
|
CP0384733
|
US9434711, 162
Show/Hide
|
C22H18BrNO3S2
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0512128
|
1-[(3-Methyl-benzo[b]thiophen-2-yl)-(4-trifluoromethoxy-benzyl)-sulfamoyl]-piperidine-4-carboxylic acid
Show/Hide
|
C23H23F3N2O5S2
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0531522
|
US9434711, 175
Show/Hide
|
C21H16BrNO2S2
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0492963
|
US9434711, 686
Show/Hide
|
C23H14F5NO4S2
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0565765
|
US9434711, 797
Show/Hide
|
C19H16BrF4NO2S2
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0419657
|
US9409915, 97
Show/Hide
|
C21H20Cl2FN5O
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0495352
|
US9434711, 538
Show/Hide
|
C20H17ClF3NO4S2
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0385824
|
2-(2-fluoroanilino)-1-[(2S)-2-phenylpyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H22F4N2O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0903797
|
(RS)-2-(2-fluorophenylamino)-1-(2-phenylpyrrolidin-1-yl)-2-(4-(trifluoromethyl)phenyl)ethanone
Show/Hide
|
C25H22F4N2O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0474771
|
US9434711, 427
Show/Hide
|
C24H16F5NO4S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0480824
|
US9434711, 393
Show/Hide
|
C21H22BrNO4S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0480825
|
US9434711, 401
Show/Hide
|
C22H25NO5S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0495351
|
US9434711, 527
Show/Hide
|
C22H15F4NO4S3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0529042
|
US9434711, 668
Show/Hide
|
C19H18BrF3N2O2S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0531489
|
US9434711, 396
Show/Hide
|
C20H18BrNO4S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0535806
|
US9434711, 415
Show/Hide
|
C27H23F4NO5S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0537411
|
US9434711, 325
Show/Hide
|
C23H15F6NO3S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0537423
|
US9434711, 15
Show/Hide
|
C20H15F2NO2S3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0563144
|
US9434711, 221
Show/Hide
|
C19H19F2NO3S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0563453
|
US9434711, 717
Show/Hide
|
C20H21BrN2O4S3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0567893
|
US9434711, 125
Show/Hide
|
C22H17F2NO2S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0572314
|
US9434711, 400
Show/Hide
|
C21H21NO4S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0572461
|
US9434711, 643
Show/Hide
|
C21H24N2O4S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0530433
|
US9434711, 758
Show/Hide
|
C21H21F4NO3S2
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
|
CP0561073
|
US9067935, 116
Show/Hide
|
C23H17ClF3N3O5S
|
1
|
| 1 |
IC50 = 5.29 nM
|
|
|
|
CP0556985
|
US9067935, 5
Show/Hide
|
C21H15BrF3N3O3S
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0539959
|
US9409915, 61
Show/Hide
|
C25H26ClF3N6O
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0507262
|
US9434711, 290
Show/Hide
|
C22H14BrF4NO3S2
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0518491
|
US9434711, 748
Show/Hide
|
C22H25F3N2O2S2
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0530431
|
US9434711, 724
Show/Hide
|
C20H17F4NO3S2
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0539962
|
US9409915, 103
Show/Hide
|
C21H19Cl3N5NaO
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0445005
|
US9434711, 41
Show/Hide
|
C18H17F2NO2S2
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0479860
|
US9067935, 96
Show/Hide
|
C24H16ClF4N5O2S
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0526154
|
US9409915, 9
Show/Hide
|
C22H20ClF3N5NaO
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0556689
|
US9067935, 11
Show/Hide
|
C22H18F3N3O3S
|
1
|
| 1 |
IC50 = 5.68 nM
|
|
|
|
CP0930220
|
US9067935, 107
Show/Hide
|
C23H18F3N3O5S
|
1
|
| 1 |
IC50 = 5.68 nM
|
|
|
|
CP0512125
|
Morpholine-1-sulfonic acid (3-methyl-benzo[b]thiophen-2-yl)-(4-trifluoromethoxy-benzyl)-amide
Show/Hide
|
C21H21F3N2O4S2
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0445006
|
US9434711, 177
Show/Hide
|
C22H14BrF4NO2S2
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0493201
|
US9434711, 772
Show/Hide
|
C25H17F3N2O4S2
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0539961
|
US9409915, 76
Show/Hide
|
C24H25ClF3N5O2
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0480815
|
US9434711, 291
Show/Hide
|
C22H14BrF4NO3S2
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0379734
|
2-(5-(2-(Trifluoromethyl)phenyl)-1H-benzo[d]imidazol-2-yl)-3-oxa-1-azaspiro[4.5]dec-1-ene
Show/Hide
|
C22H20F3N3O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0499782
|
(2S)-2-(2-fluoroanilino)-1-[(2S)-2-(2-fluorophenyl)pyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H21F5N2O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0515129
|
US9409915, 8
Show/Hide
|
C20H17F3N5NaO2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0451367
|
US9434711, 16
Show/Hide
|
C21H16F3NO3S3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0479881
|
US9434711, 525
Show/Hide
|
C25H23NO6S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0488573
|
US9434711, 191
Show/Hide
|
C20H12ClF4NO2S3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0490978
|
US9434711, 519
Show/Hide
|
C24H17F4NO4S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0495312
|
US9434711, 12
Show/Hide
|
C21H16F2N2O2S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0495357
|
US9434711, 594
Show/Hide
|
C20H18BrN5O2S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0495373
|
US9434711, 807
Show/Hide
|
C21H20N4O4S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0507264
|
US9434711, 334
Show/Hide
|
C26H18F4N2O3S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0518521
|
US9434711, 709
Show/Hide
|
C20H17BrFNO4S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0537428
|
US9434711, 95
Show/Hide
|
C21H24N2O3S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0554393
|
US9434711, 215
Show/Hide
|
C18H15F4NO3S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0555936
|
US9434711, 398
Show/Hide
|
C20H21NO4S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0559281
|
US9434711, 651
Show/Hide
|
C22H14Br2F4N2O2S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0561200
|
US9434711, 228
Show/Hide
|
C19H15F4NO3S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0563130
|
US9434711, 20
Show/Hide
|
C25H18F2N2O2S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0566340
|
US9434711, 204
Show/Hide
|
C23H17F2NO3S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0567899
|
US9434711, 187
Show/Hide
|
C20H12ClF4NO2S3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0572469
|
US9434711, 699
Show/Hide
|
C20H19F4NO3S2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0515448
|
US9434711, 590
Show/Hide
|
C19H15F4NO4S2
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0556690
|
US9067935, 27
Show/Hide
|
C23H19F4N3O2S
|
1
|
| 1 |
IC50 = 6.11 nM
|
|
|
|
CP0480814
|
US9434711, 272
Show/Hide
|
C19H18BrNO4S2
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0507302
|
US9409915, 49
Show/Hide
|
C27H30ClF3N6O2
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0515447
|
US9434711, 585
Show/Hide
|
C17H14ClF3N2O2S2
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0567898
|
US9434711, 185
Show/Hide
|
C23H16BrF4NO3S2
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0490242
|
US9409915, 66
Show/Hide
|
C25H26ClF3N6
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0556913
|
US9067935, 51
Show/Hide
|
C24H21F4N3O2S
|
1
|
| 1 |
IC50 = 6.56 nM
|
|
|
|
CP0406606
|
US9434711, 827
Show/Hide
|
C20H22FNO4S2
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0492934
|
US9434711, 570
Show/Hide
|
C21H21N5O2S2
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0515201
|
US9434711, 613
Show/Hide
|
C22H21N3O4S2
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0523413
|
3-[5-(2-Trifluoromethylphenyl)-1H-benzimidazol-2-yl]-1,8-dioxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C21H18F3N3O2
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
|
CP0495371
|
US9434711, 776
Show/Hide
|
C21H24FNO4S2
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
|
CP0516790
|
US9434711, 539
Show/Hide
|
C20H21N5O2S2
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
|
CP0554380
|
US9434711, 100
Show/Hide
|
C21H25NO3S2
|
1
|
| 1 |
IC50 = 6.8 nM
|
|
|
|
CP0564451
|
US9434711, 800
Show/Hide
|
C27H25F3N2O4S2
|
1
|
| 1 |
IC50 = 6.8 nM
|
|
|
|
CP0531673
|
US9434711, 809
Show/Hide
|
C21H19F3N4O4S2
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0385825
|
2-(2-fluoroanilino)-1-(2-pyridin-3-ylpyrrolidin-1-yl)-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C24H21F4N3O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0565982
|
2-(2-fluoroanilino)-1-[(2S)-2-(2-fluorophenyl)pyrrolidin-1-yl]-2-(4-pyridin-3-ylphenyl)ethanone
Show/Hide
|
C29H25F2N3O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0870031
|
(RS)-1-(2-(2-fluorophenyl)pyrrolidin-1-yl)-2-(2-fluorophenylamino)-2-(4-(trifluoromethyl)phenyl)ethanone
Show/Hide
|
C25H21F5N2O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0556674
|
US9067935, 95
Show/Hide
|
C24H16ClF4N5O2S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0384720
|
US9434711, 44
Show/Hide
|
C18H18F2N2O2S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0400369
|
US9434711, 70
Show/Hide
|
C29H21F4NO3S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0419253
|
US9434711, 623
Show/Hide
|
C25H20F4N2O5S3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0474919
|
US9434711, 423
Show/Hide
|
C20H21NO5S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0480826
|
US9434711, 424
Show/Hide
|
C23H15F4N5O2S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0518522
|
US9434711, 710
Show/Hide
|
C18H12BrF4NO4S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0531480
|
US9434711, 332
Show/Hide
|
C26H19F4N3O2S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0537402
|
US9434711, 197
Show/Hide
|
C24H16BrF4NO4S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0555935
|
US9434711, 392
Show/Hide
|
C20H20BrNO4S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0561670
|
US9434711, 464
Show/Hide
|
C23H19F2NO5S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0572303
|
US9434711, 286
Show/Hide
|
C22H17F2NO3S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0859107
|
2-(2-(tetrahydro-2H-pyran-4-yl)vinyl)-5-(2-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C21H19F3N2O
|
1
|
| 1 |
IC50 = 7.1 nM
|
|
|
|
CP0921334
|
2-(2-cyclohexylvinyl)-5-o-tolyl-1H-benzo[d]imidazole
Show/Hide
|
C22H24N2
|
1
|
| 1 |
IC50 = 7.1 nM
|
|
|
|
CP0563139
|
US9434711, 149
Show/Hide
|
C20H13BrF2N2O2S2
|
1
|
| 1 |
IC50 = 7.1 nM
|
|
|
|
CP0486341
|
US9434711, 692
Show/Hide
|
C20H20Br2N2O2S2
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0495369
|
US9434711, 770
Show/Hide
|
C20H18F3NO3S2
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0517087
|
US9434711, 110
Show/Hide
|
C17H25NO3S2
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0532638
|
US9434711, 771
Show/Hide
|
C21H20BrF4NO2S2
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0572475
|
US9434711, 543
Show/Hide
|
C24H17F4N3O4S3
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0495359
|
US9434711, 615
Show/Hide
|
C18H16F3NO2S2
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0554362
|
US9434711, 7
Show/Hide
|
C22H14ClF4NO2S2
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0517241
|
US9409915, 24
Show/Hide
|
C27H29F3N8
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0483489
|
US9434711, 547
Show/Hide
|
C25H21F4NO2S2
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0495358
|
US9434711, 614
Show/Hide
|
C20H21NO2S2
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0515202
|
US9434711, 626
Show/Hide
|
C21H18BrN3O4S2
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0518489
|
US9434711, 635
Show/Hide
|
C20H18ClN5O2S2
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0561971
|
US9434711, 617
Show/Hide
|
C20H20F3NO2S2
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0561973
|
US9434711, 657
Show/Hide
|
C23H25NO5S2
|
1
|
| 1 |
IC50 = 7.5 nM
|
|
|
|
CP0526201
|
US9409915, 32
Show/Hide
|
C21H19ClF3N5
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0419247
|
US9434711, 593
Show/Hide
|
C20H20FNO4S2
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0572472
|
US9434711, 812
Show/Hide
|
C23H23F3N4O3S2
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0419266
|
US9434711, 766
Show/Hide
|
C24H18Cl2F4N2O5S3
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0482840
|
US9434711, 219
Show/Hide
|
C18H17F2NO3S2
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0529040
|
US9434711, 577
Show/Hide
|
C19H18BrNO4S2
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0561979
|
US9434711, 725
Show/Hide
|
C22H23F4NO3S2
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0572305
|
US9434711, 293
Show/Hide
|
C23H14BrF4NO4S2
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0505301
|
2-{2-[2-(1-Oxa-2-aza-spiro[4.5]dec-2-en-3-yl)-1H-benzimidazol-5-yl]-phenyl}-propan-2-ol
Show/Hide
|
C24H27N3O2
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0572453
|
US9434711, 583
Show/Hide
|
C21H17BrF3N3O4S2
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0557755
|
US9067935, 54
Show/Hide
|
C24H22F3N3O2S
|
1
|
| 1 |
IC50 = 7.92 nM
|
|
|
|
CP0540288
|
2-(1-benzothiophen-2-yl)-2-(2-fluoroanilino)-1-(2-pyridin-2-ylpyrrolidin-1-yl)ethanone
Show/Hide
|
C25H22FN3OS
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0850870
|
(RS)-1-((S)-2-(2-fluorophenyl)pyrrolidin-1-yl)-2-(2-fluorophenylamino)-2-(4-(trifluoromethyl)phenyl)ethanone
Show/Hide
|
C25H21F5N2O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0497627
|
US9434711, 284
Show/Hide
|
C18H26N2O4S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0406612
|
US9434711, 479
Show/Hide
|
C20H18ClNO4S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0444955
|
US9434711, 474
Show/Hide
|
C19H16BrN5O2S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0474900
|
US9434711, 210
Show/Hide
|
C19H15F4NO3S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0517088
|
US9434711, 127
Show/Hide
|
C22H16F3NO2S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0537386
|
US9434711, 460
Show/Hide
|
C24H17F4NO5S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0554392
|
US9434711, 196
Show/Hide
|
C24H16ClF4NO4S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0564452
|
US9434711, 802
Show/Hide
|
C21H22F3NO4S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0567894
|
US9434711, 137
Show/Hide
|
C25H19F4NO4S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0572313
|
US9434711, 397
Show/Hide
|
C22H24BrNO5S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0565009
|
US9067935, 28
Show/Hide
|
C23H19F4N3O2S
|
1
|
| 1 |
IC50 = 8.01 nM
|
|
|
|
CP0486337
|
US9434711, 666
Show/Hide
|
C19H18ClF3N2O2S2
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0578158
|
US9409915, 18
Show/Hide
|
C25H26ClN5O
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0406614
|
US9434711, 537
Show/Hide
|
C19H15ClF3NO4S2
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0560157
|
US9067935, 70
Show/Hide
|
C24H19F4N3O2S
|
1
|
| 1 |
IC50 = 8.21 nM
|
|
|
|
CP0480812
|
US9434711, 248
Show/Hide
|
C20H22BrNO2S2
|
1
|
| 1 |
IC50 = 8.3 nM
|
|
|
|
CP0554389
|
US9434711, 173
Show/Hide
|
C22H15BrF3NO3S2
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0472816
|
US9067935, 97
Show/Hide
|
C24H17ClF3N5O3S
|
1
|
| 1 |
IC50 = 8.48 nM
|
|
|
|
CP0569117
|
N-(3-Bromo-benzo[b]thiophen-2-yl)-N-(4-fluoro-3-trifluorobenzyl)-(N-hexanoic acid)-sulfonamide
Show/Hide
|
C21H19BrF4N2O4S2
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0867596
|
2-(2-cyclohexylvinyl)-5-(2-fluoro-6-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C22H20F4N2
|
1
|
| 1 |
IC50 = 8.6 nM
|
|
|
|
CP0419255
|
US9434711, 627
Show/Hide
|
C21H18ClN3O4S2
|
1
|
| 1 |
IC50 = 8.6 nM
|
|
|
|
CP0474788
|
US9434711, 352
Show/Hide
|
C25H19F4NO3S2
|
1
|
| 1 |
IC50 = 8.6 nM
|
|
|
|
CP0507304
|
US9409915, 71
Show/Hide
|
C21H18Cl2F3N5
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0482804
|
US9434711, 24
Show/Hide
|
C21H14ClF2NO2S2
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0518517
|
US9434711, 579
Show/Hide
|
C20H17BrF3N5O2S2
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0554397
|
US9434711, 246
Show/Hide
|
C23H20BrNO2S2
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0859108
|
2-(2-(4-methyltetrahydro-2H-pyran-4-yl)vinyl)-5-(2-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C22H21F3N2O
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0922093
|
5-(2-chlorophenyl)-2-(2-cyclohexylvinyl)-1H-benzo[d]imidazole
Show/Hide
|
C21H21ClN2
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0922094
|
2-(2-cyclohexylvinyl)-5-(2-methoxyphenyl)-1H-benzo[d]imidazole
Show/Hide
|
C22H24N2O
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0922095
|
2-(2-(4,4-difluoro-1-methylcyclohexyl)vinyl)-5-(2-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C23H21F5N2
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0561968
|
US9434711, 600
Show/Hide
|
C18H23NO4S2
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0561980
|
US9434711, 738
Show/Hide
|
C22H26N2O2S2
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0567892
|
US9434711, 104
Show/Hide
|
C23H21NO2S2
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0385822
|
2-(4-bromophenyl)-2-(2-fluoroanilino)-1-[(2S)-2-(2-fluorophenyl)pyrrolidin-1-yl]ethanone
Show/Hide
|
C24H21BrF2N2O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0410674
|
2-(2-fluoroanilino)-1-[2-(3-fluorophenyl)pyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H21F5N2O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0419280
|
US9434711, 520
Show/Hide
|
C23H17Cl2NO4S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0451419
|
US9434711, 128
Show/Hide
|
C22H16F3NO2S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0465832
|
US9434711, 473
Show/Hide
|
C20H22BrN3O3S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0488529
|
US9434711, 371
Show/Hide
|
C22H24F3NO3S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0512583
|
US9434711, 821
Show/Hide
|
C19H20FNO3S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0517123
|
US9434711, 437
Show/Hide
|
C20H18BrNO4S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0530415
|
US9434711, 483
Show/Hide
|
C24H15F4N3O4S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0531488
|
US9434711, 394
Show/Hide
|
C19H15BrF3NO4S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0532626
|
US9434711, 716
Show/Hide
|
C20H21ClN2O4S3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0555939
|
US9434711, 459
Show/Hide
|
C23H16F4N2O3S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0572308
|
US9434711, 333
Show/Hide
|
C26H19F4N3O3S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0419264
|
US9434711, 750
Show/Hide
|
C24H27F3N2O3S2
|
1
|
| 1 |
IC50 = 9.2 nM
|
|
|
|
CP0555930
|
US9434711, 353
Show/Hide
|
C28H21F4N3O2S2
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
|
CP0563865
|
US9067935, 52
Show/Hide
|
C24H22F3N3O3S
|
1
|
| 1 |
IC50 = 9.43 nM
|
|
|
|
CP0419263
|
US9434711, 734
Show/Hide
|
C24H21BrFNO3S2
|
1
|
| 1 |
IC50 = 9.7 nM
|
|
|
|
CP0560776
|
US9067935, 34
Show/Hide
|
C23H20F3N3O2S
|
1
|
| 1 |
IC50 = 9.83 nM
|
|
|
|
CP0451207
|
2-(2-fluoroanilino)-1-[2-(2-fluorophenyl)pyrrolidin-1-yl]-2-(4-pyrimidin-5-ylphenyl)ethanone
Show/Hide
|
C28H24F2N4O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0468808
|
US9067935, 30
Show/Hide
|
C23H20F3N3O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0400365
|
US9434711, 8
Show/Hide
|
C22H15ClF3NO2S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0451423
|
US9434711, 182
Show/Hide
|
C23H16BrF4NO3S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0474904
|
US9434711, 267
Show/Hide
|
C16H23BrN2O3S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0480817
|
US9434711, 316
Show/Hide
|
C25H21F4NO3S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0493398
|
US9434711, 502
Show/Hide
|
C28H23F4NO4S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0507263
|
US9434711, 314
Show/Hide
|
C24H17F4NO3S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0531487
|
US9434711, 389
Show/Hide
|
C27H23F4NO4S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0535805
|
US9434711, 409
Show/Hide
|
C19H16F3NO4S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0537381
|
US9434711, 428
Show/Hide
|
C19H18BrN5O2S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0537403
|
US9434711, 198
Show/Hide
|
C19H14F4N2O2S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0537412
|
US9434711, 367
Show/Hide
|
C17H15F2NO2S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0554066
|
US9434711, 323
Show/Hide
|
C21H14BrF3N2O3S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0563146
|
US9434711, 234
Show/Hide
|
C20H22BrNO3S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0566322
|
US9434711, 320
Show/Hide
|
C21H12BrClF4N2O2S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0566323
|
US9434711, 322
Show/Hide
|
C21H13BrF4N2O2S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0516243
|
US9067935, 26
Show/Hide
|
C23H20F3N3O3S
|
1
|
| 1 |
IC50 = 10.1 nM
|
|
|
|
CP0540993
|
US9067935, 20
Show/Hide
|
C22H16F5N3O2S
|
1
|
| 1 |
IC50 = 10.1 nM
|
|
|
|
CP0516245
|
US9067935, 31
Show/Hide
|
C23H19F4N3O2S
|
1
|
| 1 |
IC50 = 10.3 nM
|
|
|
|
CP0492933
|
US9434711, 567
Show/Hide
|
C23H25NO4S2
|
1
|
| 1 |
IC50 = 10.3 nM
|
|
|
|
CP0565743
|
US9434711, 603
Show/Hide
|
C18H22F3NO4S2
|
1
|
| 1 |
IC50 = 10.3 nM
|
|
|
|
CP0531789
|
US9067935, 47
Show/Hide
|
C23H17F6N3O3S
|
1
|
| 1 |
IC50 = 10.4 nM
|
|
|
|
CP0565038
|
US9067935, 108
Show/Hide
|
C26H24F3N3O5S
|
1
|
| 1 |
IC50 = 10.4 nM
|
|
|
|
CP0488572
|
US9434711, 167
Show/Hide
|
C21H15BrN2O4S2
|
1
|
| 1 |
IC50 = 10.4 nM
|
|
|
|
CP0529008
|
US9434711, 618
Show/Hide
|
C20H21NO4S2
|
1
|
| 1 |
IC50 = 10.4 nM
|
|
|
|
CP0529385
|
US9434711, 158
Show/Hide
|
C21H15Cl2NO2S2
|
1
|
| 1 |
IC50 = 10.4 nM
|
|
|
|
CP0451414
|
US9434711, 42
Show/Hide
|
C19H18F3NO3S2
|
1
|
| 1 |
IC50 = 10.6 nM
|
|
|
|
CP0517163
|
US9067935, 86
Show/Hide
|
C24H20BrF4N5O3S
|
1
|
| 1 |
IC50 = 10.7 nM
|
|
|
|
CP0451602
|
US9434711, 757
Show/Hide
|
C22H21F4NO4S2
|
1
|
| 1 |
IC50 = 10.8 nM
|
|
|
|
CP0486370
|
US9434711, 541
Show/Hide
|
C21H21N3O4S2
|
1
|
| 1 |
IC50 = 10.8 nM
|
|
|
|
CP0694748
|
2-(2-cyclohexylvinyl)-5-(2-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C22H21F3N2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0870030
|
(RS)-1-(2-(2-chlorophenyl)pyrrolidin-1-yl)-2-(2-fluorophenylamino)-2-(4-(trifluoromethyl)phenyl)ethanone
Show/Hide
|
C25H21ClF4N2O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0545617
|
US9067935, 48
Show/Hide
|
C23H19F4N3O2S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0493184
|
US9409915, 12
Show/Hide
|
C21H22ClN5O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0548918
|
US9409915, 28
Show/Hide
|
C26H29ClF3N7
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0406613
|
US9434711, 510
Show/Hide
|
C20H17F4NO4S2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0495360
|
US9434711, 621
Show/Hide
|
C20H20F3NO4S2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0516733
|
US9434711, 640
Show/Hide
|
C22H20F3N3O3S3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0531479
|
US9434711, 312
Show/Hide
|
C24H16BrF4NO3S2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0554377
|
US9434711, 93
Show/Hide
|
C20H21NO4S2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0492966
|
US9434711, 804
Show/Hide
|
C20H20N6O2S2
|
1
|
| 1 |
IC50 = 11.1 nM
|
|
|
|
CP0537397
|
US9434711, 172
Show/Hide
|
C22H15BrF3NO3S2
|
1
|
| 1 |
IC50 = 11.1 nM
|
|
|
|
CP0559283
|
US9434711, 660
Show/Hide
|
C23H17BrF4N2O4S3
|
1
|
| 1 |
IC50 = 11.2 nM
|
|
|
|
CP0555174
|
US9067935, 72
Show/Hide
|
C24H20F3N3O2S
|
1
|
| 1 |
IC50 = 11.3 nM
|
|
|
|
CP0400363
|
US9434711, 6
Show/Hide
|
C22H15ClF3NO3S2
|
1
|
| 1 |
IC50 = 11.3 nM
|
|
|
|
CP0384735
|
US9434711, 166
Show/Hide
|
C21H15BrFNO2S2
|
1
|
| 1 |
IC50 = 11.4 nM
|
|
|
|
CP0531471
|
US9434711, 212
Show/Hide
|
C18H15F2NO3S2
|
1
|
| 1 |
IC50 = 11.4 nM
|
|
|
|
CP0555175
|
US9067935, 84
Show/Hide
|
C24H21BrF3N5O4S
|
1
|
| 1 |
IC50 = 11.5 nM
|
|
|
|
CP0423922
|
US9434711, 189
Show/Hide
|
C21H13ClF4N2O2S2
|
1
|
| 1 |
IC50 = 11.6 nM
|
|
|
|
CP0531475
|
US9434711, 271
Show/Hide
|
C18H13BrF3NO4S2
|
1
|
| 1 |
IC50 = 11.7 nM
|
|
|
|
CP0531720
|
US9434711, 789
Show/Hide
|
C24H22F3N3O3S2
|
1
|
| 1 |
IC50 = 11.7 nM
|
|
|
|
CP0493432
|
US9434711, 685
Show/Hide
|
C20H17F4NO4S2
|
1
|
| 1 |
IC50 = 11.9 nM
|
|
|
|
CP0408731
|
2-[1-diethoxyphosphoryl-2-(3,4-difluorophenyl)ethyl]-3-propan-2-yl-1-benzothiophene
Show/Hide
|
C23H27F2O3PS
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0540289
|
2-(2-fluoroanilino)-1-[2-(2-methoxyphenyl)pyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C26H24F4N2O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0515401
|
US9409915, 25
Show/Hide
|
C21H19ClF3N5O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0445011
|
US9434711, 305
Show/Hide
|
C24H17F4NO4S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0451432
|
US9434711, 448
Show/Hide
|
C20H25N3O2S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0507267
|
US9434711, 358
Show/Hide
|
C24H21F4N3O2S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0507271
|
US9434711, 416
Show/Hide
|
C24H29NO5S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0529038
|
US9434711, 477
Show/Hide
|
C19H18ClNO4S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0554058
|
US9434711, 458
Show/Hide
|
C24H18F4N2O3S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0554369
|
US9434711, 30
Show/Hide
|
C25H18F2N2O2S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0563141
|
US9434711, 208
Show/Hide
|
C18H13F4NO3S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0517162
|
US9067935, 80
Show/Hide
|
C24H21F4N3O2S
|
1
|
| 1 |
IC50 = 12.1 nM
|
|
|
|
CP0532565
|
US9434711, 588
Show/Hide
|
C17H13Br2F3N2O2S2
|
1
|
| 1 |
IC50 = 12.1 nM
|
|
|
|
CP0962486
|
US9067935, 120
Show/Hide
|
C23H17F4N3O5S
|
1
|
| 1 |
IC50 = 12.2 nM
|
|
|
|
CP0400375
|
US9434711, 188
Show/Hide
|
C21H13BrF4N2O2S2
|
1
|
| 1 |
IC50 = 12.2 nM
|
|
|
|
CP0493400
|
US9434711, 540
Show/Hide
|
C20H21N3O4S3
|
1
|
| 1 |
IC50 = 12.2 nM
|
|
|
|
CP0519190
|
US9434711, 637
Show/Hide
|
C20H16F3N3O3S3
|
1
|
| 1 |
IC50 = 12.2 nM
|
|
|
|
CP0531473
|
US9434711, 244
Show/Hide
|
C19H18BrNO4S2
|
1
|
| 1 |
IC50 = 12.2 nM
|
|
|
|
CP0915706
|
5-(2,6-bis(trifluoromethyl)phenyl)-2-(2-cyclohexylvinyl)-1H-benzo[d]imidazole
Show/Hide
|
C23H20F6N2
|
1
|
| 1 |
IC50 = 12.3 nM
|
|
|
|
CP0556912
|
US9067935, 50
Show/Hide
|
C24H21F4N3O2S
|
1
|
| 1 |
IC50 = 12.3 nM
|
|
|
|
CP0540994
|
US9067935, 32
Show/Hide
|
C23H19F4N3O2S
|
1
|
| 1 |
IC50 = 12.5 nM
|
|
|
|
CP0555940
|
US9434711, 261
Show/Hide
|
C14H18BrNO2S2
|
1
|
| 1 |
IC50 = 12.6 nM
|
|
|
|
CP0554398
|
US9434711, 250
Show/Hide
|
C17H13BrF3NO2S2
|
1
|
| 1 |
IC50 = 12.7 nM
|
|
|
|
CP0572309
|
US9434711, 344
Show/Hide
|
C23H27NO4S2
|
1
|
| 1 |
IC50 = 12.7 nM
|
|
|
|
CP0519187
|
US9434711, 616
Show/Hide
|
C19H18F3NO2S2
|
1
|
| 1 |
IC50 = 12.8 nM
|
|
|
|
CP0531486
|
US9434711, 386
Show/Hide
|
C24H16BrF4NO3S2
|
1
|
| 1 |
IC50 = 12.8 nM
|
|
|
|
CP0480810
|
US9434711, 230
Show/Hide
|
C22H24BrNO4S2
|
1
|
| 1 |
IC50 = 12.9 nM
|
|
|
|
CP0531253
|
4-(2,2,2-Trifluoro-ethyl)-piperazine-1-sulfonic acid (3-methyl-benzo[b]thiophen-2-yl)-(4-trifluoromethoxy-benzyl)-sulfamoyl]-amide
Show/Hide
|
C23H23F6N3O3S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0507300
|
US9409915, 2
Show/Hide
|
C22H21ClF3N5O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0419261
|
US9434711, 708
Show/Hide
|
C19H13BrF3N3O3S3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0488575
|
US9434711, 199
Show/Hide
|
C22H17F4N3O2S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0495343
|
US9434711, 480
Show/Hide
|
C18H13ClF3NO4S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0497626
|
US9434711, 833
Show/Hide
|
C19H18FNO3S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0507259
|
US9434711, 206
Show/Hide
|
C22H15F2NO3S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0531481
|
US9434711, 342
Show/Hide
|
C21H21NO5S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0554383
|
US9434711, 138
Show/Hide
|
C25H19F4NO4S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0559282
|
US9434711, 653
Show/Hide
|
C22H16F4N2O2S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0572471
|
US9434711, 806
Show/Hide
|
C20H19F3N6O2S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0557754
|
US9067935, 49
Show/Hide
|
C23H19F4N3O2S
|
1
|
| 1 |
IC50 = 13.3 nM
|
|
|
|
CP0451364
|
US9434711, 732
Show/Hide
|
C23H18BrNO3S2
|
1
|
| 1 |
IC50 = 13.3 nM
|
|
|
|
CP0545616
|
US9067935, 24
Show/Hide
|
C21H15F4N3O2S
|
1
|
| 1 |
IC50 = 13.37 nM
|
|
|
|
CP0488570
|
US9434711, 159
Show/Hide
|
C21H15BrClNO2S2
|
1
|
| 1 |
IC50 = 13.4 nM
|
|
|
|
CP0512584
|
US9434711, 733
Show/Hide
|
C23H16BrClFNO3S2
|
1
|
| 1 |
IC50 = 13.4 nM
|
|
|
|
CP0519188
|
US9434711, 624
Show/Hide
|
C20H18BrN3O4S3
|
1
|
| 1 |
IC50 = 13.4 nM
|
|
|
|
CP0518264
|
US9067935, 46
Show/Hide
|
C21H16Cl2FN3O2S
|
1
|
| 1 |
IC50 = 13.6 nM
|
|
|
|
CP0563861
|
US9067935, 9
Show/Hide
|
C21H14ClF4N3O3S
|
1
|
| 1 |
IC50 = 13.6 nM
|
|
|
|
CP0516762
|
US9434711, 765
Show/Hide
|
C21H19F4NO4S2
|
1
|
| 1 |
IC50 = 13.6 nM
|
|
|
|
CP0554370
|
US9434711, 40
Show/Hide
|
C19H17F4NO2S2
|
1
|
| 1 |
IC50 = 13.7 nM
|
|
|
|
CP0859105
|
2-(2-cyclohexylvinyl)-5-(2-(trifluoromethoxy)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C22H21F3N2O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0499783
|
2-(2,3-dihydro-1-benzofuran-5-yl)-2-(2-fluoroanilino)-1-[(2S)-2-(2-fluorophenyl)pyrrolidin-1-yl]ethanone
Show/Hide
|
C26H24F2N2O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0517255
|
US9409915, 98
Show/Hide
|
C20H18ClN3OS
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0539960
|
US9409915, 64
Show/Hide
|
C25H23F3N6O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0465839
|
US9434711, 706
Show/Hide
|
C21H18BrN3O3S3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0480885
|
US9434711, 97
Show/Hide
|
C19H19NO2S2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0507266
|
US9434711, 341
Show/Hide
|
C24H31NO4S2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0517124
|
US9434711, 443
Show/Hide
|
C20H18BrN3O4S2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0531520
|
US9434711, 157
Show/Hide
|
C17H12BrF4NO2S2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0531711
|
US9434711, 641
Show/Hide
|
C22H21N3O3S3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0537399
|
US9434711, 183
Show/Hide
|
C18H14BrF4NO2S2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0554394
|
US9434711, 216
Show/Hide
|
C17H15F2NO3S2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0554792
|
US9434711, 440
Show/Hide
|
C21H20BrNO5S2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0554384
|
US9434711, 145
Show/Hide
|
C20H13BrF2N2O2S2
|
1
|
| 1 |
IC50 = 14.1 nM
|
|
|
|
CP0561661
|
US9434711, 659
Show/Hide
|
C23H17ClF4N2O4S3
|
1
|
| 1 |
IC50 = 14.1 nM
|
|
|
|
CP0561662
|
US9434711, 661
Show/Hide
|
C23H16Br2F4N2O4S3
|
1
|
| 1 |
IC50 = 14.1 nM
|
|
|
|
CP0472838
|
US9067935, 82
Show/Hide
|
C23H18ClF4N3O2S
|
1
|
| 1 |
IC50 = 14.2 nM
|
|
|
|
CP0537396
|
US9434711, 168
Show/Hide
|
C20H15BrN2O2S2
|
1
|
| 1 |
IC50 = 14.2 nM
|
|
|
|
CP0561209
|
US9434711, 245
Show/Hide
|
C19H18BrNO4S2
|
1
|
| 1 |
IC50 = 14.2 nM
|
|
|
|
CP0516777
|
US9067935, 19
Show/Hide
|
C22H17F4N3O3S
|
1
|
| 1 |
IC50 = 14.4 nM
|
|
|
|
CP0445008
|
US9434711, 193
Show/Hide
|
C24H16BrF4NO4S2
|
1
|
| 1 |
IC50 = 14.5 nM
|
|
|
|
CP0556991
|
US9067935, 113
Show/Hide
|
C23H16ClF3N3NaO5S
|
1
|
| 1 |
IC50 = 14.6 nM
|
|
|
|
CP0419289
|
US9434711, 611
Show/Hide
|
C21H21N3O4S3
|
1
|
| 1 |
IC50 = 14.6 nM
|
|
|
|
CP0563457
|
US9434711, 787
Show/Hide
|
C21H24F3N3O2S2
|
1
|
| 1 |
IC50 = 14.9 nM
|
|
|
|
CP0406609
|
US9434711, 830
Show/Hide
|
C20H22FNO3S2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0423924
|
US9434711, 203
Show/Hide
|
C19H17F2NO3S2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0445045
|
US9434711, 837
Show/Hide
|
C20H20FNO4S2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0482803
|
US9434711, 21
Show/Hide
|
C26H19F3N2O3S2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0482809
|
US9434711, 81
Show/Hide
|
C20H22ClNO3S2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0488567
|
US9434711, 98
Show/Hide
|
C18H19NO2S3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0492929
|
US9434711, 499
Show/Hide
|
C17H15F3N2O2S2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0507265
|
US9434711, 336
Show/Hide
|
C25H19ClF4N2O3S2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0561216
|
US9434711, 318
Show/Hide
|
C25H17F4NO5S2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0561978
|
US9434711, 704
Show/Hide
|
C19H14F7NO3S2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0566324
|
US9434711, 324
Show/Hide
|
C20H13BrClFN2O2S2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0479861
|
US9067935, 99
Show/Hide
|
C24H17ClF3N5O2S
|
1
|
| 1 |
IC50 = 15.1 nM
|
|
|
|
CP0537409
|
US9434711, 307
Show/Hide
|
C23H14ClF4NO4S2
|
1
|
| 1 |
IC50 = 15.1 nM
|
|
|
|
CP0423923
|
US9434711, 190
Show/Hide
|
C18H14ClF4NO2S2
|
1
|
| 1 |
IC50 = 15.2 nM
|
|
|
|
CP0531718
|
US9434711, 786
Show/Hide
|
C21H26N4O2S2
|
1
|
| 1 |
IC50 = 15.4 nM
|
|
|
|
CP0554386
|
US9434711, 150
Show/Hide
|
C19H14BrF2N3O2S2
|
1
|
| 1 |
IC50 = 15.4 nM
|
|
|
|
CP0559290
|
US9434711, 793
Show/Hide
|
C19H17F4NO3S2
|
1
|
| 1 |
IC50 = 15.5 nM
|
|
|
|
CP0445046
|
US9434711, 839
Show/Hide
|
C21H21F4NO3S2
|
1
|
| 1 |
IC50 = 15.9 nM
|
|
|
|
CP0492936
|
US9434711, 584
Show/Hide
|
C21H17ClF3N3O4S2
|
1
|
| 1 |
IC50 = 15.9 nM
|
|
|
|
CP0561632
|
US9434711, 549
Show/Hide
|
C21H20N2O2S2
|
1
|
| 1 |
IC50 = 15.9 nM
|
|
|
|
CP0563862
|
US9067935, 15
Show/Hide
|
C22H16ClF4N3O2S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0479747
|
US9409915, 5
Show/Hide
|
C21H17Cl2F3N5Na
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0483061
|
US9409915, 10
Show/Hide
|
C21H16F6N4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0507306
|
US9409915, 78
Show/Hide
|
C22H21F4N5O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0400382
|
US9434711, 269
Show/Hide
|
C13H14BrF3N2O2S2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0465837
|
US9434711, 691
Show/Hide
|
C20H20Cl2N2O2S2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0486369
|
US9434711, 528
Show/Hide
|
C23H17F4NO4S3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0567900
|
US9434711, 207
Show/Hide
|
C23H15F4NO3S2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0532620
|
US9434711, 690
Show/Hide
|
C20H21ClN2O2S2
|
1
|
| 1 |
IC50 = 16.1 nM
|
|
|
|
CP0565762
|
US9434711, 599
Show/Hide
|
C20H16F3N3O4S2
|
1
|
| 1 |
IC50 = 16.1 nM
|
|
|
|
CP0567876
|
US9434711, 2
Show/Hide
|
C20H17F2N3O2S2
|
1
|
| 1 |
IC50 = 16.3 nM
|
|
|
|
CP0532635
|
US9434711, 754
Show/Hide
|
C28H24F3NO5S2
|
1
|
| 1 |
IC50 = 16.4 nM
|
|
|
|
CP0559279
|
US9434711, 572
Show/Hide
|
C19H16F3N5O2S2
|
1
|
| 1 |
IC50 = 16.6 nM
|
|
|
|
CP0556984
|
US9067935, 4
Show/Hide
|
C16H13BrF3N3O3S
|
1
|
| 1 |
IC50 = 16.7 nM
|
|
|
|
CP0492964
|
US9434711, 773
Show/Hide
|
C22H19F3N2O3S2
|
1
|
| 1 |
IC50 = 16.7 nM
|
|
|
|
CP0563140
|
US9434711, 151
Show/Hide
|
C16H12BrF2NO2S2
|
1
|
| 1 |
IC50 = 16.7 nM
|
|
|
|
CP0480254
|
1-[(2S)-2-(2-chlorophenyl)pyrrolidin-1-yl]-2-(2-fluoroanilino)-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H21ClF4N2O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0517240
|
US9409915, 3
Show/Hide
|
C21H20ClF3N6
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0474772
|
US9434711, 434
Show/Hide
|
C20H21NO7S2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0488565
|
US9434711, 65
Show/Hide
|
C24H16F4N2O2S3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0495306
|
US9434711, 317
Show/Hide
|
C18H15BrF4N2O2S2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0507270
|
US9434711, 410
Show/Hide
|
C20H18F3NO4S2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0531482
|
US9434711, 359
Show/Hide
|
C23H18F4N2O3S2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0537414
|
US9434711, 384
Show/Hide
|
C20H17F3N2O4S2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0553439
|
US9434711, 429
Show/Hide
|
C19H15BrF3N5O2S2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0561975
|
US9434711, 695
Show/Hide
|
C24H14BrF7N2O3S2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0465826
|
US9434711, 252
Show/Hide
|
C17H16BrNO3S2
|
1
|
| 1 |
IC50 = 17.1 nM
|
|
|
|
CP0532633
|
US9434711, 736
Show/Hide
|
C24H22BrNO3S2
|
1
|
| 1 |
IC50 = 17.2 nM
|
|
|
|
CP0518490
|
US9434711, 741
Show/Hide
|
C24H28N2O3S2
|
1
|
| 1 |
IC50 = 17.3 nM
|
|
|
|
CP0426464
|
US9067935, 10
Show/Hide
|
C21H13ClF5N3O2S
|
1
|
| 1 |
IC50 = 17.4 nM
|
|
|
|
CP0573297
|
US9067935, 118
Show/Hide
|
C24H19F4N3O5S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0531597
|
N-(3-Bromo-benzo[b]thiophen-2-yl)-N-(4-fluoro-3-trifluorobenzyl)-(N-butyric acid)-sulfonamide
Show/Hide
|
C20H17BrF4N2O4S2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0414507
|
US9409915, 31
Show/Hide
|
C20H17F3N4O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0451415
|
US9434711, 75
Show/Hide
|
C22H18F4N2O2S3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0474774
|
US9434711, 452
Show/Hide
|
C19H18BrNO4S2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0488568
|
US9434711, 99
Show/Hide
|
C18H19NO3S2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0517283
|
US9434711, 723
Show/Hide
|
C25H17F4N3O2S2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0554063
|
US9434711, 273
Show/Hide
|
C19H16BrNO4S2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0554375
|
US9434711, 71
Show/Hide
|
C22H21F4NO4S2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0554378
|
US9434711, 94
Show/Hide
|
C20H21NO4S2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0554449
|
US9434711, 422
Show/Hide
|
C21H23NO5S2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0555933
|
US9434711, 368
Show/Hide
|
C18H15F4NO2S2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0565747
|
US9434711, 504
Show/Hide
|
C22H22F3NO5S2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0572311
|
US9434711, 369
Show/Hide
|
C18H16F3NO3S2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0530417
|
US9434711, 608
Show/Hide
|
C19H13BrF3N3O4S2
|
1
|
| 1 |
IC50 = 18.1 nM
|
|
|
|
CP0563864
|
US9067935, 44
Show/Hide
|
C22H17ClF3N3O2S
|
1
|
| 1 |
IC50 = 18.3 nM
|
|
|
|
CP0563456
|
US9434711, 759
Show/Hide
|
C23H25F4NO3S2
|
1
|
| 1 |
IC50 = 18.3 nM
|
|
|
|
CP0488569
|
US9434711, 153
Show/Hide
|
C18H16BrF2NO2S2
|
1
|
| 1 |
IC50 = 18.8 nM
|
|
|
|
CP0517284
|
US9434711, 768
Show/Hide
|
C21H21ClFNO3S2
|
1
|
| 1 |
IC50 = 18.8 nM
|
|
|
|
CP0572476
|
US9434711, 550
Show/Hide
|
C19H15F3N2O2S2
|
1
|
| 1 |
IC50 = 18.8 nM
|
|
|
|
CP0554367
|
US9434711, 14
Show/Hide
|
C24H19N3O2S2
|
1
|
| 1 |
IC50 = 18.9 nM
|
|
|
|
CP0451209
|
2-(2-fluoroanilino)-1-(2-pyridin-4-ylpyrrolidin-1-yl)-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C24H21F4N3O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0465867
|
US9409915, 46
Show/Hide
|
C21H19ClF3N5
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0519699
|
US9409915, 112
Show/Hide
|
C24H26F3N5O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0419249
|
US9434711, 595
Show/Hide
|
C18H13BrF3N5O2S2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0419279
|
US9434711, 516
Show/Hide
|
C23H27NO5S2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0474912
|
US9434711, 337
Show/Hide
|
C22H14ClF4N3O2S3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0474913
|
US9434711, 343
Show/Hide
|
C22H25NO5S2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0518520
|
US9434711, 705
Show/Hide
|
C17H13BrF4N2O2S2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0554983
|
US9434711, 357
Show/Hide
|
C23H18F4N2O3S2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0555934
|
US9434711, 388
Show/Hide
|
C25H20BrF4NO3S2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0563133
|
US9434711, 64
Show/Hide
|
C24H18F5NO3S2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0566334
|
US9434711, 106
Show/Hide
|
C14H16F3NO2S2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0495356
|
US9434711, 576
Show/Hide
|
C23H14BrF4N5O2S2
|
1
|
| 1 |
IC50 = 19.1 nM
|
|
|
|
CP0567897
|
US9434711, 171
Show/Hide
|
C21H15BrN2O4S2
|
1
|
| 1 |
IC50 = 19.3 nM
|
|
|
|
CP0486330
|
US9409915, 79
Show/Hide
|
C23H24F3N5O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0516725
|
US9409915, 77
Show/Hide
|
C21H21ClFN5O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0451428
|
US9434711, 431
Show/Hide
|
C22H14BrF4NO4S2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0492924
|
US9434711, 467
Show/Hide
|
C23H26N2O5S2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0554065
|
US9434711, 288
Show/Hide
|
C22H14ClF4NO3S2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0555508
|
US9434711, 27
Show/Hide
|
C25H18F2N2O2S2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0566329
|
US9434711, 26
Show/Hide
|
C23H19F2NO3S2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0444958
|
US9434711, 625
Show/Hide
|
C20H18ClN3O4S3
|
1
|
| 1 |
IC50 = 20.4 nM
|
|
|
|
CP0556986
|
US9067935, 14
Show/Hide
|
C22H17ClF3N3O3S
|
1
|
| 1 |
IC50 = 20.7 nM
|
|
|
|
CP0853888
|
2-(2-cyclohexylvinyl)-5-(2-fluorophenyl)-1H-benzo[d]imidazole
Show/Hide
|
C21H21FN2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0921335
|
2-(2-(4,4-difluorocyclohexyl)vinyl)-5-(2-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C22H19F5N2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0445043
|
US9434711, 819
Show/Hide
|
C18H18FNO2S2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0474908
|
US9434711, 313
Show/Hide
|
C26H19F4NO5S2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0480809
|
US9434711, 229
Show/Hide
|
C18H15F2NO3S2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0482805
|
US9434711, 25
Show/Hide
|
C23H19F2NO3S2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0482808
|
US9434711, 76
Show/Hide
|
C22H15ClF4N2O2S2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0495344
|
US9434711, 485
Show/Hide
|
C19H18ClN3O4S3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0517086
|
US9434711, 74
Show/Hide
|
C23H21F4N3O2S2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0531667
|
US9434711, 484
Show/Hide
|
C19H18BrN3O4S3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0559278
|
US9434711, 513
Show/Hide
|
C20H16F3N3O4S2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0572297
|
US9434711, 90
Show/Hide
|
C25H29ClN2O4S2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0561218
|
US9434711, 351
Show/Hide
|
C21H20F3NO3S2
|
1
|
| 1 |
IC50 = 21.2 nM
|
|
|
|
CP0567896
|
US9434711, 169
Show/Hide
|
C20H15BrN2O2S2
|
1
|
| 1 |
IC50 = 21.4 nM
|
|
|
|
CP0564975
|
US9067935, 71
Show/Hide
|
C24H20F3N3O3S
|
1
|
| 1 |
IC50 = 21.5 nM
|
|
|
|
CP0556990
|
US9067935, 102
Show/Hide
|
C25H18ClF4N5O2S
|
1
|
| 1 |
IC50 = 21.83 nM
|
|
|
|
CP0564107
|
US9434711, 555
Show/Hide
|
C24H18F4N2O4S2
|
1
|
| 1 |
IC50 = 21.9 nM
|
|
|
|
CP0474581
|
2-[2-(3-chlorophenyl)-1-diethoxyphosphorylethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C21H24ClO3PS
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0468810
|
US9067935, 64
Show/Hide
|
C21H21F6N3O2S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0529491
|
US9409915, 43
Show/Hide
|
C20H19ClFN5
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0428844
|
US9434711, 823
Show/Hide
|
C20H20FNO4S2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0451368
|
US9434711, 17
Show/Hide
|
C23H18N2O2S3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0495313
|
US9434711, 31
Show/Hide
|
C26H19F3N2O3S2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0495372
|
US9434711, 790
Show/Hide
|
C26H24F3N3O4S2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0507260
|
US9434711, 233
Show/Hide
|
C22H18BrNO2S2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0531474
|
US9434711, 265
Show/Hide
|
C14H19BrN2O2S2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0556716
|
US9434711, 77
Show/Hide
|
C22H15ClF4N2O2S2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0531713
|
US9434711, 764
Show/Hide
|
C20H20F3NO4S2
|
1
|
| 1 |
IC50 = 22.1 nM
|
|
|
|
CP0561659
|
US9434711, 602
Show/Hide
|
C17H20F3NO4S2
|
1
|
| 1 |
IC50 = 22.1 nM
|
|
|
|
CP0572464
|
US9434711, 580
Show/Hide
|
C20H17ClF3N5O2S2
|
1
|
| 1 |
IC50 = 22.1 nM
|
|
|
|
CP0470637
|
US9067935, 40
Show/Hide
|
C23H19F4N3O2S
|
1
|
| 1 |
IC50 = 22.2 nM
|
|
|
|
CP0556661
|
US9067935, 36
Show/Hide
|
C22H17ClF3N3O3S
|
1
|
| 1 |
IC50 = 22.5 nM
|
|
|
|
CP0402745
|
US9409915, 94
Show/Hide
|
C20H18ClF3N6O
|
1
|
| 1 |
IC50 = 22.5 nM
|
|
|
|
CP0563126
|
US9434711, 78
Show/Hide
|
C20H13F4NO2S3
|
1
|
| 1 |
IC50 = 22.5 nM
|
|
|
|
CP0406607
|
US9434711, 829
Show/Hide
|
C17H17FN2O2S2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0519196
|
US9434711, 702
Show/Hide
|
C18H11BrF7NO2S2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0559287
|
US9434711, 719
Show/Hide
|
C22H23BrN2O4S3
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0561976
|
US9434711, 696
Show/Hide
|
C28H23F4NO4S2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0530444
|
US9434711, 791
Show/Hide
|
C20H17F4NO4S2
|
1
|
| 1 |
IC50 = 23.1 nM
|
|
|
|
CP0530432
|
US9434711, 739
Show/Hide
|
C24H30N2O2S2
|
1
|
| 1 |
IC50 = 23.2 nM
|
|
|
|
CP0493429
|
US9434711, 628
Show/Hide
|
C22H23NO4S2
|
1
|
| 1 |
IC50 = 23.3 nM
|
|
|
|
CP0499631
|
US9434711, 620
Show/Hide
|
C19H18F3NO4S2
|
1
|
| 1 |
IC50 = 23.4 nM
|
|
|
|
CP0490877
|
US9434711, 730
Show/Hide
|
C23H17BrFNO3S2
|
1
|
| 1 |
IC50 = 23.6 nM
|
|
|
|
CP0564976
|
US9067935, 119
Show/Hide
|
C24H18F5N3O4S
|
1
|
| 1 |
IC50 = 23.9 nM
|
|
|
|
CP0410791
|
2-[2-(3,4-difluorophenyl)-1-di(propan-2-yloxy)phosphorylethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C23H27F2O3PS
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0490241
|
US9409915, 56
Show/Hide
|
C24H28Cl2N6O
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0490244
|
US9409915, 110
Show/Hide
|
C19H18Cl2N6
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0507305
|
US9409915, 75
Show/Hide
|
C22H18ClF3N6
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0419278
|
US9434711, 505
Show/Hide
|
C21H20F3NO5S2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0451474
|
US9434711, 826
Show/Hide
|
C22H16F3NO2S2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0492925
|
US9434711, 482
Show/Hide
|
C23H17F4N3O3S2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0517099
|
US9434711, 319
Show/Hide
|
C21H12BrClF4N2O2S2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0517117
|
US9434711, 1
Show/Hide
|
C21H15F2NO2S2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0529044
|
US9434711, 715
Show/Hide
|
C18H16BrF3N2O4S3
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0531670
|
US9434711, 836
Show/Hide
|
C19H21FN2O3S2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0555510
|
US9434711, 85
Show/Hide
|
C22H18ClNO2S2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0518265
|
US9067935, 63
Show/Hide
|
C21H22F3N3O2S
|
1
|
| 1 |
IC50 = 24.1 nM
|
|
|
|
CP0419250
|
US9434711, 601
Show/Hide
|
C16H18F3NO4S2
|
1
|
| 1 |
IC50 = 24.1 nM
|
|
|
|
CP0565764
|
US9434711, 796
Show/Hide
|
C22H24F3NO4S2
|
1
|
| 1 |
IC50 = 24.2 nM
|
|
|
|
CP0472836
|
US9067935, 43
Show/Hide
|
C22H17ClF3N3O2S
|
1
|
| 1 |
IC50 = 24.3 nM
|
|
|
|
CP0563871
|
US9067935, 103
Show/Hide
|
C25H18ClF4N5O2S
|
1
|
| 1 |
IC50 = 24.5 nM
|
|
|
|
CP0444960
|
US9434711, 677
Show/Hide
|
C18H16BrF3N2O4S3
|
1
|
| 1 |
IC50 = 24.6 nM
|
|
|
|
CP0492965
|
US9434711, 795
Show/Hide
|
C20H18F3NO5S2
|
1
|
| 1 |
IC50 = 24.6 nM
|
|
|
|
CP0531472
|
US9434711, 237
Show/Hide
|
C20H21BrN2O3S2
|
1
|
| 1 |
IC50 = 24.8 nM
|
|
|
|
CP0462415
|
2-(2-fluoroanilino)-1-[2-(2-fluorophenyl)pyrrolidin-1-yl]-2-(4-pyridin-4-ylphenyl)ethanone
Show/Hide
|
C29H25F2N3O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0483956
|
2-(2-fluoroanilino)-1-(2-pyridin-2-ylpyrrolidin-1-yl)-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C24H21F4N3O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0540287
|
2-(1-benzothiophen-2-yl)-2-(2-fluoroanilino)-1-(2-pyridin-3-ylpyrrolidin-1-yl)ethanone
Show/Hide
|
C25H22FN3OS
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0556989
|
US9067935, 89
Show/Hide
|
C26H21ClF3N5O3S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0560967
|
US9067935, 92
Show/Hide
|
C24H21ClF3N5O4S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0517244
|
US9409915, 60
Show/Hide
|
C22H18ClF3N6
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0384719
|
US9434711, 43
Show/Hide
|
C18H15F4NO2S2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0519495
|
US9434711, 825
Show/Hide
|
C22H17F2NO2S2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0531707
|
US9434711, 478
Show/Hide
|
C19H16ClNO4S2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0518516
|
US9434711, 552
Show/Hide
|
C21H19F3N2O2S2
|
1
|
| 1 |
IC50 = 25.1 nM
|
|
|
|
CP0572452
|
US9434711, 581
Show/Hide
|
C20H17BrF3N3O4S3
|
1
|
| 1 |
IC50 = 25.1 nM
|
|
|
|
CP0465838
|
US9434711, 693
Show/Hide
|
C20H21BrN2O2S2
|
1
|
| 1 |
IC50 = 25.2 nM
|
|
|
|
CP0426465
|
US9067935, 41
Show/Hide
|
C23H19F4N3O2S
|
1
|
| 1 |
IC50 = 25.3 nM
|
|
|
|
CP0495367
|
US9434711, 762
Show/Hide
|
C20H18F3NO5S2
|
1
|
| 1 |
IC50 = 25.3 nM
|
|
|
|
CP0540996
|
US9067935, 42
Show/Hide
|
C23H18BrF4N3O2S
|
1
|
| 1 |
IC50 = 25.4 nM
|
|
|
|
CP0517091
|
US9434711, 247
Show/Hide
|
C16H14BrNO2S2
|
1
|
| 1 |
IC50 = 25.5 nM
|
|
|
|
CP0495364
|
US9434711, 683
Show/Hide
|
C18H15Br2F3N2O4S3
|
1
|
| 1 |
IC50 = 25.8 nM
|
|
|
|
CP0444959
|
US9434711, 676
Show/Hide
|
C18H16ClF3N2O4S3
|
1
|
| 1 |
IC50 = 25.9 nM
|
|
|
|
CP0529050
|
US9434711, 788
Show/Hide
|
C23H26F3N3O3S2
|
1
|
| 1 |
IC50 = 25.9 nM
|
|
|
|
CP0410789
|
3-cyclopentyl-2-[1-diethoxyphosphoryl-2-(3,4-difluorophenyl)ethyl]-1-benzothiophene
Show/Hide
|
C25H29F2O3PS
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0490254
|
US9409915, 23
Show/Hide
|
C20H19Cl2N5
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0423912
|
US9434711, 23
Show/Hide
|
C21H15ClFNO2S2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0445015
|
US9434711, 376
Show/Hide
|
C24H16F5NO4S2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0535818
|
US9434711, 463
Show/Hide
|
C25H21F4NO5S2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0563134
|
US9434711, 72
Show/Hide
|
C22H17F4N3O4S2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0474787
|
US9434711, 339
Show/Hide
|
C22H23NO5S2
|
1
|
| 1 |
IC50 = 26.2 nM
|
|
|
|
CP0493197
|
US9434711, 629
Show/Hide
|
C20H18F3NO4S2
|
1
|
| 1 |
IC50 = 26.2 nM
|
|
|
|
CP0419257
|
US9434711, 631
Show/Hide
|
C22H22F3NO4S2
|
1
|
| 1 |
IC50 = 26.3 nM
|
|
|
|
CP0554067
|
US9434711, 345
Show/Hide
|
C17H17BrN2O2S2
|
1
|
| 1 |
IC50 = 26.5 nM
|
|
|
|
CP0540995
|
US9067935, 33
Show/Hide
|
C23H20F3N3O2S
|
1
|
| 1 |
IC50 = 26.7 nM
|
|
|
|
CP0561966
|
US9434711, 578
Show/Hide
|
C23H14ClF4N5O2S2
|
1
|
| 1 |
IC50 = 26.7 nM
|
|
|
|
CP0451365
|
US9434711, 735
Show/Hide
|
C25H21BrF3NO4S2
|
1
|
| 1 |
IC50 = 26.8 nM
|
|
|
|
CP0546011
|
US9067935, 90
Show/Hide
|
C24H20ClF4N5O3S
|
1
|
| 1 |
IC50 = 26.9 nM
|
|
|
|
CP0563870
|
US9067935, 93
Show/Hide
|
C24H21ClF3N5O3S
|
1
|
| 1 |
IC50 = 26.9 nM
|
|
|
|
CP0419656
|
US9409915, 95
Show/Hide
|
C20H18ClF3N6
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0490240
|
US9409915, 45
Show/Hide
|
C22H19F3N6
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0507298
|
US9409915, 1
Show/Hide
|
C22H18ClF6N5
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0518456
|
US9409915, 53
Show/Hide
|
C25H28ClF3N6O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0444952
|
US9434711, 372
Show/Hide
|
C24H21F3N2O3S2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0517096
|
US9434711, 289
Show/Hide
|
C22H14ClF4NO3S2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0529045
|
US9434711, 753
Show/Hide
|
C27H22F3NO5S2
|
1
|
| 1 |
IC50 = 27.2 nM
|
|
|
|
CP0561210
|
US9434711, 253
Show/Hide
|
C19H18BrNO3S2
|
1
|
| 1 |
IC50 = 27.3 nM
|
|
|
|
CP0495368
|
US9434711, 763
Show/Hide
|
C22H24F3NO4S2
|
1
|
| 1 |
IC50 = 27.7 nM
|
|
|
|
CP0414511
|
US9409915, 73
Show/Hide
|
C20H16ClF3N4O
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0419658
|
US9409915, 105
Show/Hide
|
C20H18ClN3OS
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0445034
|
US9434711, 813
Show/Hide
|
C21H13ClF4N2O2S2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0563442
|
US9434711, 820
Show/Hide
|
C18H18FNO3S2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0565011
|
US9067935, 69
Show/Hide
|
C24H19F4N3O2S
|
1
|
| 1 |
IC50 = 28.2 nM
|
|
|
|
CP0555509
|
US9434711, 60
Show/Hide
|
C22H18FNO3S2
|
1
|
| 1 |
IC50 = 28.3 nM
|
|
|
|
CP0479880
|
US9434711, 561
Show/Hide
|
C20H23ClN2O2S2
|
1
|
| 1 |
IC50 = 28.4 nM
|
|
|
|
CP0517161
|
US9067935, 39
Show/Hide
|
C23H20F3N3O3S
|
1
|
| 1 |
IC50 = 28.9 nM
|
|
|
|
CP0515197
|
US9434711, 548
Show/Hide
|
C22H25NO2S2
|
1
|
| 1 |
IC50 = 28.9 nM
|
|
|
|
CP0451416
|
US9434711, 80
Show/Hide
|
C21H22ClNO2S2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0465960
|
US9434711, 714
Show/Hide
|
C18H16ClF3N2O4S3
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0517101
|
US9434711, 338
Show/Hide
|
C21H12Cl2F4N2O2S2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0537383
|
US9434711, 450
Show/Hide
|
C20H20FNO4S2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0563127
|
US9434711, 231
Show/Hide
|
C18H18BrNO2S2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0419243
|
US9067935, 37
Show/Hide
|
C22H16ClF4N3O2S
|
1
|
| 1 |
IC50 = 29.4 nM
|
|
|
|
CP0428843
|
US9434711, 794
Show/Hide
|
C21H20F3NO5S2
|
1
|
| 1 |
IC50 = 29.4 nM
|
|
|
|
CP0567872
|
US9434711, 355
Show/Hide
|
C27H21F4N3O3S2
|
1
|
| 1 |
IC50 = 29.6 nM
|
|
|
|
CP0516776
|
US9067935, 7
Show/Hide
|
C21H14Cl2F3N3O3S
|
1
|
| 1 |
IC50 = 29.8 nM
|
|
|
|
CP0563147
|
US9434711, 287
Show/Hide
|
C21H17NO3S2
|
1
|
| 1 |
IC50 = 29.8 nM
|
|
|
|
CP0444939
|
US9434711, 737
Show/Hide
|
C24H20BrClFNO3S2
|
1
|
| 1 |
IC50 = 29.9 nM
|
|
|
|
CP0553267
|
2-anilino-1-[2-(2-fluorophenyl)pyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H22F4N2O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0516724
|
US9409915, 62
Show/Hide
|
C22H21ClF3N5O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0474770
|
US9434711, 426
Show/Hide
|
C20H17F4NO4S2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0537406
|
US9434711, 256
Show/Hide
|
C21H23BrN2O2S2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0563142
|
US9434711, 211
Show/Hide
|
C25H17F4NO5S2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0559284
|
US9434711, 667
Show/Hide
|
C19H17Cl2F3N2O2S2
|
1
|
| 1 |
IC50 = 30.1 nM
|
|
|
|
CP0566335
|
US9434711, 112
Show/Hide
|
C15H19NO2S2
|
1
|
| 1 |
IC50 = 30.2 nM
|
|
|
|
CP0419252
|
US9067935, 105
Show/Hide
|
C25H19ClF3N5O2S
|
1
|
| 1 |
IC50 = 30.3 nM
|
|
|
|
CP0563135
|
US9434711, 101
Show/Hide
|
C18H17NO4S2
|
1
|
| 1 |
IC50 = 30.5 nM
|
|
|
|
CP0564115
|
US9434711, 598
Show/Hide
|
C19H16F3N3O4S3
|
1
|
| 1 |
IC50 = 30.7 nM
|
|
|
|
CP0564453
|
US9434711, 803
Show/Hide
|
C21H20F3NO3S2
|
1
|
| 1 |
IC50 = 30.8 nM
|
|
|
|
CP0860110
|
2-(2-(tetrahydro-2H-thiopyran-4-yl)vinyl)-5-(2-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C21H19F3N2S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0410786
|
2-[1-diethoxyphosphoryl-2-(3-fluorophenyl)ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C21H24FO3PS
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0537416
|
US9434711, 387
Show/Hide
|
C25H16F4N2O3S2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0561649
|
US9434711, 506
Show/Hide
|
C21H24BrNO3S2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0554503
|
US9067935, 85
Show/Hide
|
C24H20BrF4N5O3S
|
1
|
| 1 |
IC50 = 31.2 nM
|
|
|
|
CP0444957
|
US9434711, 622
Show/Hide
|
C23H17F4NO4S2
|
1
|
| 1 |
IC50 = 31.3 nM
|
|
|
|
CP0406617
|
US9434711, 682
Show/Hide
|
C20H18Cl3F3N2O4S3
|
1
|
| 1 |
IC50 = 31.7 nM
|
|
|
|
CP0529494
|
US9409915, 99
Show/Hide
|
C21H20ClN3O2
|
1
|
| 1 |
IC50 = 31.8 nM
|
|
|
|
CP0384734
|
US9434711, 164
Show/Hide
|
C22H18BrNO3S2
|
1
|
| 1 |
IC50 = 31.9 nM
|
|
|
|
CP0423909
|
US9434711, 209
Show/Hide
|
C17H13F2NO3S2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0492931
|
US9434711, 533
Show/Hide
|
C18H16F4N2O2S2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0531506
|
US9434711, 28
Show/Hide
|
C26H19F3N2O3S2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0556715
|
US9434711, 22
Show/Hide
|
C28H21N3O2S2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0561963
|
US9434711, 509
Show/Hide
|
C24H18F4N2O3S2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0516244
|
US9067935, 29
Show/Hide
|
C21H13Cl2F4N3O2S
|
1
|
| 1 |
IC50 = 32.2 nM
|
|
|
|
CP0561977
|
US9434711, 701
Show/Hide
|
C29H27F3N4O3S2
|
1
|
| 1 |
IC50 = 32.5 nM
|
|
|
|
CP0949754
|
US9067935, 121
Show/Hide
|
C23H16F5N3O4S
|
1
|
| 1 |
IC50 = 32.8 nM
|
|
|
|
CP0426822
|
3-[(2S)-1-[2-(2-fluoroanilino)-2-[4-(trifluoromethyl)phenyl]acetyl]pyrrolidin-2-yl]benzoic acid
Show/Hide
|
C26H22F4N2O3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0473455
|
2-anilino-1-[2-(2-methoxyphenyl)pyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C26H25F3N2O2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0529490
|
US9409915, 29
Show/Hide
|
C20H17F3N4O2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0517098
|
US9434711, 295
Show/Hide
|
C23H15F4NO4S2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0517122
|
US9434711, 435
Show/Hide
|
C19H18BrNO6S2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0537382
|
US9434711, 433
Show/Hide
|
C20H20BrNO6S2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0554368
|
US9434711, 29
Show/Hide
|
C28H21N3O2S2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0563129
|
US9434711, 11
Show/Hide
|
C21H18F3N3O3S2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0495354
|
US9434711, 562
Show/Hide
|
C22H25ClN2O3S2
|
1
|
| 1 |
IC50 = 33.1 nM
|
|
|
|
CP0472837
|
US9067935, 55
Show/Hide
|
C24H18F7N3O2S
|
1
|
| 1 |
IC50 = 33.4 nM
|
|
|
|
CP0529495
|
US9409915, 101
Show/Hide
|
C21H19BrClN3O2
|
1
|
| 1 |
IC50 = 33.9 nM
|
|
|
|
CP0531708
|
US9434711, 507
Show/Hide
|
C18H17F3N2O4S3
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0400381
|
US9434711, 264
Show/Hide
|
C16H22BrNO3S2
|
1
|
| 1 |
IC50 = 34.1 nM
|
|
|
|
CP0565744
|
US9434711, 671
Show/Hide
|
C14H13F6NO2S2
|
1
|
| 1 |
IC50 = 34.5 nM
|
|
|
|
CP0497613
|
US9434711, 586
Show/Hide
|
C17H14ClF3N2O2S2
|
1
|
| 1 |
IC50 = 34.6 nM
|
|
|
|
CP0540982
|
US9067935, 115
Show/Hide
|
C23H15ClF4N3NaO4S
|
1
|
| 1 |
IC50 = 34.9 nM
|
|
|
|
CP0490255
|
US9409915, 26
Show/Hide
|
C19H17ClN4O
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0400370
|
US9434711, 84
Show/Hide
|
C17H14ClNO2S2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0400376
|
US9434711, 3
Show/Hide
|
C21H16FNO2S2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0493426
|
US9434711, 569
Show/Hide
|
C20H19N5O2S2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0563138
|
US9434711, 121
Show/Hide
|
C16H21NO3S2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0566325
|
US9434711, 328
Show/Hide
|
C22H16F7N3O2S2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0400374
|
US9434711, 178
Show/Hide
|
C22H18BrNO2S2
|
1
|
| 1 |
IC50 = 35.5 nM
|
|
|
|
CP0561972
|
US9434711, 630
Show/Hide
|
C21H20F3NO4S2
|
1
|
| 1 |
IC50 = 35.6 nM
|
|
|
|
CP0567895
|
US9434711, 160
Show/Hide
|
C22H18BrNO3S2
|
1
|
| 1 |
IC50 = 35.8 nM
|
|
|
|
CP0530445
|
US9434711, 798
Show/Hide
|
C23H27N3O3S2
|
1
|
| 1 |
IC50 = 35.9 nM
|
|
|
|
CP0474906
|
US9434711, 274
Show/Hide
|
C18H16BrNO5S2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0554428
|
US9434711, 399
Show/Hide
|
C20H19NO4S2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0555938
|
US9434711, 405
Show/Hide
|
C22H17BrN2O4S2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0561220
|
US9434711, 455
Show/Hide
|
C24H17F4N5O2S2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0554388
|
US9434711, 154
Show/Hide
|
C19H18BrF2NO2S2
|
1
|
| 1 |
IC50 = 36.2 nM
|
|
|
|
CP0561970
|
US9434711, 607
Show/Hide
|
C18H13BrF3N3O4S3
|
1
|
| 1 |
IC50 = 36.8 nM
|
|
|
|
CP0451210
|
2-(2-fluoroanilino)-1-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H21F5N2O
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0526203
|
US9409915, 44
Show/Hide
|
C21H19FN6
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0480819
|
US9434711, 327
Show/Hide
|
C23H17F4NO5S2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0531507
|
US9434711, 32
Show/Hide
|
C28H21N3O2S2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0572312
|
US9434711, 375
Show/Hide
|
C25H18F5NO4S2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0563867
|
US9067935, 73
Show/Hide
|
C24H20F3N3O2S
|
1
|
| 1 |
IC50 = 37.2 nM
|
|
|
|
CP0859106
|
2-(2-cyclohexylvinyl)-5-(3-(trifluoromethyl)pyridin-2-yl)-1H-benzo[d]imidazole
Show/Hide
|
C21H20F3N3
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0515128
|
US9409915, 7
Show/Hide
|
C20H16ClF3N4O
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0516773
|
US9434711, 824
Show/Hide
|
C19H18FNO4S2
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0554396
|
US9434711, 243
Show/Hide
|
C17H14BrNO4S2
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0561213
|
US9434711, 280
Show/Hide
|
C16H23NO3S2
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0561208
|
US9434711, 242
Show/Hide
|
C16H12BrF2NO2S2
|
1
|
| 1 |
IC50 = 38.2 nM
|
|
|
|
CP0400379
|
US9434711, 251
Show/Hide
|
C19H16BrNO2S2
|
1
|
| 1 |
IC50 = 38.7 nM
|
|
|
|
CP0384849
|
US9067935, 45
Show/Hide
|
C22H17ClF3N3O3S
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0554062
|
US9434711, 266
Show/Hide
|
C14H17BrN2O2S2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0554064
|
US9434711, 277
Show/Hide
|
C21H21BrN2O5S2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0559285
|
US9434711, 670
Show/Hide
|
C16H18F3NO2S2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0563454
|
US9434711, 718
Show/Hide
|
C22H23ClN2O4S3
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0419251
|
US9434711, 619
Show/Hide
|
C18H16F3NO4S2
|
1
|
| 1 |
IC50 = 39.8 nM
|
|
|
|
CP0917557
|
(RS)-3-(1-(2-(2-fluorophenylamino)-2-(4-(trifluoromethyl)phenyl)acetyl)pyrrolidin-2-yl)benzoic acid
Show/Hide
|
C26H22F4N2O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0545029
|
US9409915, 33
Show/Hide
|
C20H19ClFN5
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0480821
|
US9434711, 366
Show/Hide
|
C16H23NO3S2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0493200
|
US9434711, 761
Show/Hide
|
C20H18F3NO5S2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0561961
|
US9434711, 472
Show/Hide
|
C22H25N3O4S2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0451418
|
US9434711, 102
Show/Hide
|
C17H15F2NO2S2
|
1
|
| 1 |
IC50 = 40.2 nM
|
|
|
|
CP0385823
|
4-[1-[2-(1-benzothiophen-2-yl)-2-(2-fluoroanilino)acetyl]pyrrolidin-2-yl]benzoic acid
Show/Hide
|
C27H23FN2O3S
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0385826
|
2-anilino-1-[(2S)-2-(2-chlorophenyl)pyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H22ClF3N2O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0474790
|
US9434711, 360
Show/Hide
|
C24H21F4N3O2S2
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0559280
|
US9434711, 642
Show/Hide
|
C21H19N3O3S3
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0560159
|
US9067935, 88
Show/Hide
|
C26H20ClF4N5O2S
|
1
|
| 1 |
IC50 = 41.4 nM
|
|
|
|
CP0531792
|
US9067935, 91
Show/Hide
|
C24H20ClF4N5O3S
|
1
|
| 1 |
IC50 = 41.6 nM
|
|
|
|
CP0517102
|
US9434711, 356
Show/Hide
|
C23H21F3N2O3S2
|
1
|
| 1 |
IC50 = 41.6 nM
|
|
|
|
CP0556988
|
US9067935, 68
Show/Hide
|
C23H18F5N3O2S
|
1
|
| 1 |
IC50 = 41.64 nM
|
|
|
|
CP0518762
|
US9409915, 80
Show/Hide
|
C22H22F3N5O
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0519496
|
US9434711, 828
Show/Hide
|
C18H18FNO3S2
|
1
|
| 1 |
IC50 = 42.7 nM
|
|
|
|
CP0422522
|
2-(2-fluoroanilino)-1-[(2R)-2-phenylpyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H22F4N2O
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0444953
|
US9434711, 407
Show/Hide
|
C17H14BrF3N2O2S2
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0445007
|
US9434711, 180
Show/Hide
|
C23H16ClF4NO3S2
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0572310
|
US9434711, 346
Show/Hide
|
C21H22F4N2O2S2
|
1
|
| 1 |
IC50 = 43.8 nM
|
|
|
|
CP0526533
|
2-(2-fluoroanilino)-1-[(2R)-2-(2-fluorophenyl)pyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H21F5N2O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0507268
|
US9434711, 364
Show/Hide
|
C13H14F3NO2S2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0531714
|
US9434711, 769
Show/Hide
|
C20H19BrF3NO3S2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0518523
|
US9434711, 731
Show/Hide
|
C24H17BrF3NO4S2
|
1
|
| 1 |
IC50 = 44.4 nM
|
|
|
|
CP0451422
|
US9434711, 170
Show/Hide
|
C20H15BrN2O2S2
|
1
|
| 1 |
IC50 = 44.5 nM
|
|
|
|
CP0554372
|
US9434711, 59
Show/Hide
|
C21H17NO2S2
|
1
|
| 1 |
IC50 = 44.5 nM
|
|
|
|
CP0563863
|
US9067935, 35
Show/Hide
|
C18H17F4N3O2S
|
1
|
| 1 |
IC50 = 44.9 nM
|
|
|
|
CP0462414
|
(2R)-2-(2-fluoroanilino)-1-[(2S)-2-(2-fluorophenyl)pyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H21F5N2O
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0488564
|
US9434711, 58
Show/Hide
|
C22H16F3NO3S2
|
1
|
| 1 |
IC50 = 45.5 nM
|
|
|
|
CP0559288
|
US9434711, 760
Show/Hide
|
C21H20F3NO5S2
|
1
|
| 1 |
IC50 = 45.9 nM
|
|
|
|
CP0512126
|
4-Methyl-piperazine-1-sulfonic acid (3-methyl-benzo[b]thiophen-2-yl)-(4-trifluoromethoxy-benzyl)-sulfamoyl]-amide
Show/Hide
|
C22H24F3N3O3S2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0548917
|
US9409915, 13
Show/Hide
|
C22H18F3N5O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0493198
|
US9434711, 636
Show/Hide
|
C18H13ClF3N5O2S2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0531490
|
US9434711, 413
Show/Hide
|
C23H16F4N2O3S2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0539241
|
US9434711, 514
Show/Hide
|
C20H15BrF3N3O4S2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0572473
|
US9434711, 531
Show/Hide
|
C21H19ClF3NO4S2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0500942
|
US9434711, 503
Show/Hide
|
C20H20BrNO3S2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0537417
|
US9434711, 391
Show/Hide
|
C18H16BrNO4S2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0554363
|
US9434711, 9
Show/Hide
|
C20H14F2N2O2S2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0554793
|
US9434711, 457
Show/Hide
|
C25H20F4N2O3S2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0537401
|
US9434711, 195
Show/Hide
|
C24H16ClF4NO4S2
|
1
|
| 1 |
IC50 = 47.3 nM
|
|
|
|
CP0400372
|
US9434711, 118
Show/Hide
|
C21H23NO2S2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0488566
|
US9434711, 83
Show/Hide
|
C18H18ClNO2S2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0555515
|
US9434711, 131
Show/Hide
|
C21H14F3NO2S2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0556717
|
US9434711, 146
Show/Hide
|
C21H14F4N2O2S2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0479879
|
US9434711, 556
Show/Hide
|
C19H19NO4S2
|
1
|
| 1 |
IC50 = 48.2 nM
|
|
|
|
CP0479859
|
US9067935, 94
Show/Hide
|
C24H21ClF3N5O3S
|
1
|
| 1 |
IC50 = 48.4 nM
|
|
|
|
CP0472834
|
US9067935, 12
Show/Hide
|
C21H16F3N3O3S
|
1
|
| 1 |
IC50 = 48.7 nM
|
|
|
|
CP0531715
|
US9434711, 779
Show/Hide
|
C24H23F4N3O2S2
|
1
|
| 1 |
IC50 = 48.7 nM
|
|
|
|
CP0490763
|
US9067935, 13
Show/Hide
|
C21H15F4N3O2S
|
1
|
| 1 |
IC50 = 48.9 nM
|
|
|
|
CP0516772
|
US9434711, 822
Show/Hide
|
C20H22FNO3S2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0493403
|
US9434711, 563
Show/Hide
|
C27H23F4NO4S2
|
1
|
| 1 |
IC50 = 49.3 nM
|
|
|
|
CP0530460
|
US9434711, 831
Show/Hide
|
C18H16F3NO2S2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0554399
|
US9434711, 260
Show/Hide
|
C17H16BrNO2S3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0531669
|
US9434711, 582
Show/Hide
|
C20H17ClF3N3O4S3
|
1
|
| 1 |
IC50 = 50.3 nM
|
|
|
|
CP0526202
|
US9409915, 41
Show/Hide
|
C20H20ClN5
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0419260
|
US9434711, 703
Show/Hide
|
C18H11ClF7NO2S2
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0555932
|
US9434711, 363
Show/Hide
|
C14H19NO2S2
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0563136
|
US9434711, 114
Show/Hide
|
C21H30N2O4S2
|
1
|
| 1 |
IC50 = 51.1 nM
|
|
|
|
CP0561663
|
US9434711, 669
Show/Hide
|
C19H14F7NO2S2
|
1
|
| 1 |
IC50 = 51.2 nM
|
|
|
|
CP0463390
|
US9067935, 104
Show/Hide
|
C25H19ClF3N5O3S
|
1
|
| 1 |
IC50 = 51.6 nM
|
|
|
|
CP0531508
|
US9434711, 45
Show/Hide
|
C17H13F4NO2S2
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0537427
|
US9434711, 61
Show/Hide
|
C22H15F4NO2S2
|
1
|
| 1 |
IC50 = 52.4 nM
|
|
|
|
CP0563449
|
US9434711, 689
Show/Hide
|
C21H24N2O2S2
|
1
|
| 1 |
IC50 = 52.8 nM
|
|
|
|
CP0451417
|
US9434711, 86
Show/Hide
|
C21H23ClN2O4S2
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0474918
|
US9434711, 404
Show/Hide
|
C19H19NO4S2
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0419258
|
US9434711, 656
Show/Hide
|
C22H23BrF3NO3S2
|
1
|
| 1 |
IC50 = 53.7 nM
|
|
|
|
CP0492938
|
US9434711, 612
Show/Hide
|
C21H19N3O4S2
|
1
|
| 1 |
IC50 = 53.7 nM
|
|
|
|
CP0515200
|
US9434711, 609
Show/Hide
|
C19H13ClF3N3O4S2
|
1
|
| 1 |
IC50 = 53.7 nM
|
|
|
|
CP0554381
|
US9434711, 117
Show/Hide
|
C18H19NO2S2
|
1
|
| 1 |
IC50 = 53.7 nM
|
|
|
|
CP0516723
|
US9409915, 55
Show/Hide
|
C27H33Cl2N7O
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0465836
|
US9434711, 495
Show/Hide
|
C22H18N2O4S2
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0537410
|
US9434711, 309
Show/Hide
|
C17H13ClF4N2O2S2
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0566331
|
US9434711, 67
Show/Hide
|
C25H18F4N2O4S2
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0539935
|
US9434711, 835
Show/Hide
|
C18H19FN2O3S2
|
1
|
| 1 |
IC50 = 55.1 nM
|
|
|
|
CP0488571
|
US9434711, 161
Show/Hide
|
C22H17Br2NO3S2
|
1
|
| 1 |
IC50 = 55.4 nM
|
|
|
|
CP0565985
|
4-[4-[1-(2-fluoroanilino)-2-[(2S)-2-(2-fluorophenyl)pyrrolidin-1-yl]-2-oxoethyl]phenyl]benzoic acid
Show/Hide
|
C31H26F2N2O3
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0545001
|
US9409915, 50
Show/Hide
|
C28H33ClF3N7O
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0495363
|
US9434711, 680
Show/Hide
|
C20H20BrF3N2O4S3
|
1
|
| 1 |
IC50 = 56.1 nM
|
|
|
|
CP0518518
|
US9434711, 687
Show/Hide
|
C21H18F3N3O3S3
|
1
|
| 1 |
IC50 = 56.9 nM
|
|
|
|
CP0400387
|
US9434711, 347
Show/Hide
|
C20H20F4N2O2S2
|
1
|
| 1 |
IC50 = 57.1 nM
|
|
|
|
CP0562155
|
US9067935, 110
Show/Hide
|
C24H19ClF3N3O5S
|
1
|
| 1 |
IC50 = 57.2 nM
|
|
|
|
CP0561981
|
US9434711, 744
Show/Hide
|
C24H19ClF4N2O5S3
|
1
|
| 1 |
IC50 = 57.3 nM
|
|
|
|
CP0495314
|
US9434711, 33
Show/Hide
|
C20H14F2N2O2S2
|
1
|
| 1 |
IC50 = 57.4 nM
|
|
|
|
CP0565746
|
US9434711, 679
Show/Hide
|
C20H20ClF3N2O4S3
|
1
|
| 1 |
IC50 = 57.9 nM
|
|
|
|
CP0410788
|
2-[1-diethoxyphosphoryl-2-(3,5-difluorophenyl)ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C21H23F2O3PS
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0563132
|
US9434711, 62
Show/Hide
|
C22H19NO2S2
|
1
|
| 1 |
IC50 = 58.1 nM
|
|
|
|
CP0490238
|
US9409915, 40
Show/Hide
|
C21H20F3N5
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0490239
|
US9409915, 42
Show/Hide
|
C20H20FN5
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0495342
|
US9434711, 471
Show/Hide
|
C20H23N3O3S2
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0422524
|
2-anilino-1-(2-phenylpyrrolidin-1-yl)-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H23F3N2O
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0560933
|
4-Isopropyl-piperazine-1-sulfonic acid (3-methyl-benzo[b]thiophen-2-yl)-(4-trifluoromethoxy-benzyl)-sulfamoyl]-amide
Show/Hide
|
C24H28F3N3O3S2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0384731
|
US9434711, 133
Show/Hide
|
C17H15F2NO4S3
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0529009
|
US9434711, 638
Show/Hide
|
C20H18FNO4S2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0537400
|
US9434711, 192
Show/Hide
|
C24H16BrF4NO4S2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0419259
|
US9434711, 688
Show/Hide
|
C20H22N2O2S2
|
1
|
| 1 |
IC50 = 60.2 nM
|
|
|
|
CP0488559
|
US9434711, 35
Show/Hide
|
C17H15F2NO2S2
|
1
|
| 1 |
IC50 = 60.8 nM
|
|
|
|
CP0517151
|
2-(5-(2-(Trifluoromethyl)phenyl)-1H-benzimidazol-2-yl)-1-oxa-3-azaspiro[4.5]dec-2-ene
Show/Hide
|
C22H20F3N3O
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0572318
|
1-[(3-Methyl-benzo[b]thiophen-2-yl)-(4-trifluoromethoxy-benzyl)-sulfamoyl]-piperidine-4-carboxylic acid (2-dimethylamino-ethyl)-amide
Show/Hide
|
C27H33F3N4O4S2
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0546861
|
US9409915, 100
Show/Hide
|
C21H22ClN5O
|
1
|
| 1 |
IC50 = 61.3 nM
|
|
|
|
CP0412083
|
N-(4-Fluoro-3-trifluoromethyl-benzyl)-N-(3-methyl-benzo[b]-thiophen-2-yl)-N′-(butyric acid)-sulfonamide
Show/Hide
|
C21H20F4N2O4S2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0482837
|
US9434711, 139
Show/Hide
|
C24H17F4NO4S2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0492928
|
US9434711, 492
Show/Hide
|
C24H21NO6S3
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0537419
|
US9434711, 417
Show/Hide
|
C24H20F4N2O2S2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0559293
|
US9434711, 818
Show/Hide
|
C17H16FNO2S2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0531790
|
US9067935, 67
Show/Hide
|
C23H19F4N3O3S
|
1
|
| 1 |
IC50 = 62.1 nM
|
|
|
|
CP0563868
|
US9067935, 74
Show/Hide
|
C24H19Cl2F4N5O3S
|
1
|
| 1 |
IC50 = 62.6 nM
|
|
|
|
CP0565010
|
US9067935, 65
Show/Hide
|
C20H20F3N3O2S
|
1
|
| 1 |
IC50 = 62.8 nM
|
|
|
|
CP0490962
|
US9409915, 72
Show/Hide
|
C25H23ClF3N5
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0451434
|
US9434711, 465
Show/Hide
|
C21H22N2O5S2
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0563128
|
US9434711, 5
Show/Hide
|
C24H17ClN2O2S2
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0451420
|
US9434711, 163
Show/Hide
|
C22H17Br2NO3S2
|
1
|
| 1 |
IC50 = 63.9 nM
|
|
|
|
CP0523679
|
2-[1-diethoxyphosphoryl-2-(3,4-difluorophenyl)ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C21H23F2O3PS
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0474909
|
US9434711, 315
Show/Hide
|
C18H16F4N2O2S2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0495365
|
US9434711, 697
Show/Hide
|
C18H12F7NO2S2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0517104
|
US9434711, 421
Show/Hide
|
C22H15F4NO4S2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0444311
|
2-[1-diethoxyphosphoryl-2-(3-methylphenyl)ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C22H27O3PS
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0557728
|
US9067935, 56
Show/Hide
|
C24H18F7N3O2S
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0400367
|
US9434711, 55
Show/Hide
|
C21H16N2O4S2
|
1
|
| 1 |
IC50 = 65.5 nM
|
|
|
|
CP0495353
|
US9434711, 560
Show/Hide
|
C20H23BrN2O2S2
|
1
|
| 1 |
IC50 = 65.7 nM
|
|
|
|
CP0445143
|
4-[1-[2-(2-fluoroanilino)-2-[4-(trifluoromethyl)phenyl]acetyl]pyrrolidin-2-yl]benzoic acid
Show/Hide
|
C26H22F4N2O3
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0563131
|
US9434711, 50
Show/Hide
|
C21H16FNO2S2
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0400380
|
US9434711, 262
Show/Hide
|
C14H16BrNO2S2
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0572316
|
US9434711, 442
Show/Hide
|
C20H19N3O4S2
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0444989
|
US9434711, 681
Show/Hide
|
C18H14Cl3F3N2O4S3
|
1
|
| 1 |
IC50 = 67.4 nM
|
|
|
|
CP0537384
|
US9434711, 451
Show/Hide
|
C19H16F3NO4S2
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0384725
|
US9434711, 92
Show/Hide
|
C20H21ClN2O3S2
|
1
|
| 1 |
IC50 = 68.2 nM
|
|
|
|
CP0531710
|
US9434711, 546
Show/Hide
|
C24H16F4N2O2S2
|
1
|
| 1 |
IC50 = 68.3 nM
|
|
|
|
CP0492888
|
US9409915, 6
Show/Hide
|
C21H19ClF3N5
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0517119
|
US9434711, 418
Show/Hide
|
C25H22F4N2O2S2
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0561215
|
US9434711, 308
Show/Hide
|
C24H17F4NO3S2
|
1
|
| 1 |
IC50 = 69.8 nM
|
|
|
|
CP0561214
|
US9434711, 282
Show/Hide
|
C15H18F3NO3S2
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0561217
|
US9434711, 321
Show/Hide
|
C21H12Cl2F4N2O2S2
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0563869
|
US9067935, 76
Show/Hide
|
C24H20Cl2F3N5O4S
|
1
|
| 1 |
IC50 = 70.5 nM
|
|
|
|
CP0569116
|
4-(3-Methyl-butyl)-piperazine-1-sulfonic acid (3-methyl-benzo[b]thiophen-2-yl)-(4-trifluoromethoxy-benzyl)-sulfamoyl]-amide
Show/Hide
|
C26H32F3N3O3S2
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0444950
|
US9434711, 276
Show/Hide
|
C17H12BrF2NO4S2
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0516246
|
US9067935, 58
Show/Hide
|
C24H19F6N3O2S
|
1
|
| 1 |
IC50 = 71.5 nM
|
|
|
|
CP0557747
|
US9067935, 16
Show/Hide
|
C20H14Cl2FN3O2S
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0414509
|
US9409915, 51
Show/Hide
|
C26H30Cl2N6O
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0473454
|
1-[2-(2-chlorophenyl)pyrrolidin-1-yl]-2-(4-fluoroanilino)-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H21ClF4N2O
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0495374
|
US9434711, 817
Show/Hide
|
C17H16FNO2S2
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0565745
|
US9434711, 673
Show/Hide
|
C16H17F6NO2S2
|
1
|
| 1 |
IC50 = 73.8 nM
|
|
|
|
CP0531512
|
US9434711, 63
Show/Hide
|
C22H19NO2S2
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0563145
|
US9434711, 232
Show/Hide
|
C21H22BrNO2S2
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0565039
|
US9067935, 17
Show/Hide
|
C20H15Cl2N3O2S
|
1
|
| 1 |
IC50 = 74.3 nM
|
|
|
|
CP0531791
|
US9067935, 83
Show/Hide
|
C23H22BrN5O3S
|
1
|
| 1 |
IC50 = 74.6 nM
|
|
|
|
CP0486338
|
US9434711, 672
Show/Hide
|
C15H15F6NO2S2
|
1
|
| 1 |
IC50 = 74.9 nM
|
|
|
|
CP0490961
|
US9409915, 39
Show/Hide
|
C21H20F3N5O
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0490237
|
US9409915, 34
Show/Hide
|
C21H20F3N5
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0572474
|
US9434711, 536
Show/Hide
|
C21H24N2O6S2
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0507257
|
US9434711, 36
Show/Hide
|
C18H17F2NO2S2
|
1
|
| 1 |
IC50 = 77.1 nM
|
|
|
|
CP0555173
|
US9067935, 66
Show/Hide
|
C19H17F6N3O2S
|
1
|
| 1 |
IC50 = 77.4 nM
|
|
|
|
CP0495362
|
US9434711, 674
Show/Hide
|
C27H21F4NO4S2
|
1
|
| 1 |
IC50 = 77.6 nM
|
|
|
|
CP0553263
|
3-[1-[2-(1-benzothiophen-2-yl)-2-(2-fluoroanilino)acetyl]pyrrolidin-2-yl]benzoic acid
Show/Hide
|
C27H23FN2O3S
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0488561
|
US9434711, 51
Show/Hide
|
C21H16N2O4S2
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0529384
|
US9434711, 147
Show/Hide
|
C20H14F2N2O2S2
|
1
|
| 1 |
IC50 = 78.2 nM
|
|
|
|
CP0565008
|
US9067935, 18
Show/Hide
|
C20H13Cl2F2N3O2S
|
1
|
| 1 |
IC50 = 78.6 nM
|
|
|
|
CP0486324
|
US9409915, 52
Show/Hide
|
C27H30ClF3N6O
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0482806
|
US9434711, 48
Show/Hide
|
C22H19NO3S2
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0507273
|
US9434711, 425
Show/Hide
|
C19H16F3N5O2S2
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0480886
|
US9434711, 115
Show/Hide
|
C22H19NO2S2
|
1
|
| 1 |
IC50 = 79.5 nM
|
|
|
|
CP0556914
|
US9067935, 59
Show/Hide
|
C24H19F6N3O2S
|
1
|
| 1 |
IC50 = 80.2 nM
|
|
|
|
CP0529416
|
US9434711, 18
Show/Hide
|
C24H17F2NO2S3
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0419254
|
US9067935, 111
Show/Hide
|
C23H18ClF2N3O4S
|
1
|
| 1 |
IC50 = 81.5 nM
|
|
|
|
CP0419256
|
US9067935, 112
Show/Hide
|
C24H18ClF4N3O4S
|
1
|
| 1 |
IC50 = 82.1 nM
|
|
|
|
CP0531509
|
US9434711, 46
Show/Hide
|
C21H16ClNO2S2
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0554390
|
US9434711, 181
Show/Hide
|
C23H16ClF4NO3S2
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0563455
|
US9434711, 745
Show/Hide
|
C22H23N3O2S2
|
1
|
| 1 |
IC50 = 84.9 nM
|
|
|
|
CP0495361
|
US9434711, 652
Show/Hide
|
C23H18F4N2O4S3
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0474903
|
US9434711, 255
Show/Hide
|
C18H16BrNO2S2
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0384850
|
US9067935, 87
Show/Hide
|
C26H24ClF4N5O3S
|
1
|
| 1 |
IC50 = 86.3 nM
|
|
|
|
CP0495544
|
US9409915, 30
Show/Hide
|
C19H17FN4O
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0515207
|
US9434711, 832
Show/Hide
|
C19H20FNO3S2
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0517100
|
US9434711, 330
Show/Hide
|
C22H14BrClF4N2O2S2
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0535817
|
US9434711, 449
Show/Hide
|
C19H19N5O2S2
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0483488
|
US9434711, 551
Show/Hide
|
C20H17F3N2O2S2
|
1
|
| 1 |
IC50 = 88.6 nM
|
|
|
|
CP0419267
|
US9434711, 767
Show/Hide
|
C27H24F4N2O2S2
|
1
|
| 1 |
IC50 = 89.2 nM
|
|
|
|
CP0566326
|
US9434711, 331
Show/Hide
|
C22H14Cl2F4N2O2S2
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0564450
|
US9434711, 726
Show/Hide
|
C21H21N3O2S2
|
1
|
| 1 |
IC50 = 90.3 nM
|
|
|
|
CP0561969
|
US9434711, 606
Show/Hide
|
C17H20F3NO4S2
|
1
|
| 1 |
IC50 = 90.5 nM
|
|
|
|
CP0555513
|
US9434711, 103
Show/Hide
|
C25H30N2O4S2
|
1
|
| 1 |
IC50 = 90.8 nM
|
|
|
|
CP0523409
|
3-[5-(2,2-Difluorobenzo[1,3]dioxol-4-yl)-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
Show/Hide
|
C22H19F2N3O3
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0400371
|
US9434711, 111
Show/Hide
|
C13H15F2NO2S2
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0507261
|
US9434711, 239
Show/Hide
|
C17H16BrNO4S3
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0531477
|
US9434711, 283
Show/Hide
|
C18H27NO4S2
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0572301
|
US9434711, 238
Show/Hide
|
C18H19BrN2O2S2
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0548952
|
US9409915, 74
Show/Hide
|
C21H19ClF3N5
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0474870
|
US9434711, 446
Show/Hide
|
C22H26N2O3S2
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0530420
|
US9434711, 729
Show/Hide
|
C24H18F3N3O3S2
|
1
|
| 1 |
IC50 = 96.2 nM
|
|
|
|
CP0563866
|
US9067935, 57
Show/Hide
|
C24H19F6N3O3S
|
1
|
| 1 |
IC50 = 96.6 nM
|
|
|
|
CP0537413
|
US9434711, 378
Show/Hide
|
C23H18F4N2O2S3
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0495378
|
US9434711, 840
Show/Hide
|
C17H15F3N2O2S2
|
1
|
| 1 |
IC50 = 98.1 nM
|
|
|
|
CP0488560
|
US9434711, 37
Show/Hide
|
C19H19F2NO2S2
|
1
|
| 1 |
IC50 = 98.3 nM
|
|
|
|
CP0515198
|
US9434711, 558
Show/Hide
|
C21H20F3NO4S2
|
1
|
| 1 |
IC50 = 99.4 nM
|
|
|
|
CP0423917
|
US9434711, 116
Show/Hide
|
C17H15NO2S2
|
1
|
| 1 |
IC50 = 101.7 nM
|
|
|
|
CP0488563
|
US9434711, 56
Show/Hide
|
C22H16F3NO3S2
|
1
|
| 1 |
IC50 = 103.1 nM
|
|
|
|
CP0554382
|
US9434711, 130
Show/Hide
|
C19H15F2N3O2S2
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0474902
|
US9434711, 241
Show/Hide
|
C20H21BrN2O2S2
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0561219
|
US9434711, 354
Show/Hide
|
C24H22F3N3O2S2
|
1
|
| 1 |
IC50 = 106.4 nM
|
|
|
|
CP0559289
|
US9434711, 778
Show/Hide
|
C23H22F3N3O3S2
|
1
|
| 1 |
IC50 = 106.9 nM
|
|
|
|
CP0531511
|
US9434711, 57
Show/Hide
|
C22H16F3NO3S2
|
1
|
| 1 |
IC50 = 108 nM
|
|
|
|
CP0853887
|
2-(2-cyclohexylvinyl)-5-phenyl-1H-benzo[d]imidazole
Show/Hide
|
C21H22N2
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0878987
|
2-(2-cyclopentylvinyl)-5-(2-(trifluoromethoxy)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C21H19F3N2O
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0554371
|
US9434711, 47
Show/Hide
|
C22H19NO3S2
|
1
|
| 1 |
IC50 = 112 nM
|
|
|
|
CP0444310
|
2-[1-diethoxyphosphoryl-2-(2-fluorophenyl)ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C21H24FO3PS
|
1
|
| 1 |
IC50 = 114 nM
|
|
|
|
CP0537615
|
3-cyclopropyl-2-[1-diethoxyphosphoryl-2-(3,4-difluorophenyl)ethyl]-1-benzothiophene
Show/Hide
|
C23H25F2O3PS
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0488562
|
US9434711, 52
Show/Hide
|
C20H16N2O2S2
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0444985
|
US9434711, 565
Show/Hide
|
C24H26F3NO4S2
|
1
|
| 1 |
IC50 = 117 nM
|
|
|
|
CP0408725
|
2-[1-diethoxyphosphoryl-2-[4-fluoro-3-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C22H23F4O3PS
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0432114
|
2-[1-diethoxyphosphoryl-2-(4-fluorophenyl)ethyl]naphthalene
Show/Hide
|
C22H24FO3P
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0451565
|
US9409915, 81
Show/Hide
|
C22H22F3N5O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0529496
|
US9409915, 102
Show/Hide
|
C20H20ClN5O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0408728
|
2-[1-diethoxyphosphoryl-2-(3-methoxyphenyl)ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C22H27O4PS
|
1
|
| 1 |
IC50 = 121 nM
|
|
|
|
CP0451431
|
US9434711, 444
Show/Hide
|
C20H24N2O2S2
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0537418
|
US9434711, 408
Show/Hide
|
C17H14ClF3N2O2S2
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0444316
|
2-[1-[bis(2-methylpropyl)phosphoryl]-2-(3,4-difluorophenyl)ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C25H31F2OPS
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0531483
|
US9434711, 373
Show/Hide
|
C24H21F3N2O3S2
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0559294
|
US9434711, 834
Show/Hide
|
C22H15Br2F2NO3S2
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0414473
|
US9409915, 27
Show/Hide
|
C20H20ClN5
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0482848
|
US9434711, 254
Show/Hide
|
C18H19BrNO5PS2
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0519191
|
US9434711, 639
Show/Hide
|
C18H13F4NO4S2
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0513059
|
US9409915, 87
Show/Hide
|
C22H21Cl2N5O3
|
1
|
| 1 |
IC50 = 131 nM
|
|
|
|
CP0563137
|
US9434711, 119
Show/Hide
|
C20H21NO2S2
|
1
|
| 1 |
IC50 = 133.6 nM
|
|
|
|
CP0408724
|
2-[1-diethoxyphosphoryl-2-[3-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C22H24F3O3PS
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0528660
|
1-[2-(2-chlorophenyl)pyrrolidin-1-yl]-2-(3-fluoroanilino)-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H21ClF4N2O
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0564454
|
US9434711, 814
Show/Hide
|
C22H13ClF4N2O4S2
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0444990
|
US9434711, 684
Show/Hide
|
C19H14F3N3O3S3
|
1
|
| 1 |
IC50 = 144.8 nM
|
|
|
|
CP0522504
|
2-[2-(3-bromophenyl)-1-diethoxyphosphorylethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C21H24BrO3PS
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0531716
|
US9434711, 780
Show/Hide
|
C23H17ClF4N2O5S3
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0408726
|
3-cyclobutyl-2-[1-diethoxyphosphoryl-2-(3,4-difluorophenyl)ethyl]-1-benzothiophene
Show/Hide
|
C24H27F2O3PS
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0531478
|
US9434711, 311
Show/Hide
|
C21H13ClF4N2O2S2
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0400373
|
US9434711, 120
Show/Hide
|
C17H17NO2S3
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0444315
|
2-[1-diethoxyphosphoryl-2-(3,4-difluorophenyl)ethyl]-3-(2,2-dimethylpropyl)-1-benzothiophene
Show/Hide
|
C25H31F2O3PS
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0531510
|
US9434711, 53
Show/Hide
|
C20H16N2O2S2
|
1
|
| 1 |
IC50 = 164 nM
|
|
|
|
CP0444314
|
2-[2-(3,4-difluorophenyl)-1-dipropylphosphorylethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C23H27F2OPS
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0473357
|
2-anilino-1-[(2R)-2-(2-chlorophenyl)pyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
Show/Hide
|
C25H22ClF3N2O
|
1
|
| 1 |
IC50 = 168 nM
|
|
|
|
CP0482807
|
US9434711, 49
Show/Hide
|
C22H19NO3S2
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0566333
|
US9434711, 87
Show/Hide
|
C18H19ClN2O2S2
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0410790
|
2-[1-diethoxyphosphoryl-2-(4-fluorophenyl)ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C21H24FO3PS
|
1
|
| 1 |
IC50 = 184 nM
|
|
|
|
CP0561199
|
US9434711, 34
Show/Hide
|
C16H13F2NO2S2
|
1
|
| 1 |
IC50 = 184.1 nM
|
|
|
|
CP0517095
|
US9434711, 263
Show/Hide
|
C12H12BrF2NO2S2
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0482810
|
US9434711, 89
Show/Hide
|
C24H27ClN2O4S2
|
1
|
| 1 |
IC50 = 205 nM
|
|
|
|
CP0554365
|
US9434711, 10
Show/Hide
|
C23H20N4O2S2
|
1
|
| 1 |
IC50 = 229 nM
|
|
|
|
CP0410787
|
2-[1-diethoxyphosphoryl-2-[4-(trifluoromethoxy)phenyl]ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C22H24F3O4PS
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0461356
|
2-[1-diethoxyphosphoryl-2-(4-fluorophenyl)ethyl]-1-benzothiophene
Show/Hide
|
C20H22FO3PS
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0554376
|
US9434711, 88
Show/Hide
|
C17H16ClNO4S3
|
1
|
| 1 |
IC50 = 261 nM
|
|
|
|
CP0444312
|
2-[2-(3,4-dichlorophenyl)-1-diethoxyphosphorylethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C21H23Cl2O3PS
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0566332
|
US9434711, 82
Show/Hide
|
C20H19ClN2O3S2
|
1
|
| 1 |
IC50 = 319 nM
|
|
|
|
CP0537407
|
US9434711, 270
Show/Hide
|
C16H15ClN2O2S2
|
1
|
| 1 |
IC50 = 338 nM
|
|
|
|
CP0507272
|
US9434711, 419
Show/Hide
|
C21H21NO5S2
|
1
|
| 1 |
IC50 = 345 nM
|
|
|
|
CP0444313
|
3-cyclohexyl-2-[1-diethoxyphosphoryl-2-(3,4-difluorophenyl)ethyl]-1-benzothiophene
Show/Hide
|
C26H31F2O3PS
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0410785
|
2-(1-diethoxyphosphoryl-2-phenylethyl)-3-methyl-1-benzothiophene
Show/Hide
|
C21H25O3PS
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0523678
|
2-[1-diethoxyphosphoryl-2-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C22H24F3O3PS
|
1
|
| 1 |
IC50 = 365 nM
|
|
|
|
CP0408730
|
2-[1-diethoxyphosphoryl-2-(3,4-difluorophenyl)ethyl]-1-benzothiophene
Show/Hide
|
C20H21F2O3PS
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0408727
|
1-[1-diethoxyphosphoryl-2-(4-fluorophenyl)ethyl]naphthalene
Show/Hide
|
C22H24FO3P
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0410784
|
2-[1-diethoxyphosphoryl-2-(4-fluorophenyl)ethyl]-1-benzofuran
Show/Hide
|
C20H22FO4P
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0523672
|
2-[2-[4-chloro-3-(trifluoromethyl)phenyl]-1-diethoxyphosphorylethyl]-3-methyl-1-benzothiophene
Show/Hide
|
C22H23ClF3O3PS
|
1
|
| 1 |
IC50 = 525 nM
|
|
|
|
CP0444309
|
3-[1-diethoxyphosphoryl-2-(4-fluorophenyl)ethyl]-5-fluoro-1-benzothiophene
Show/Hide
|
C20H21F2O3PS
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0537616
|
1-bromo-4-(2-diethoxyphosphoryl-2-phenylethyl)benzene
Show/Hide
|
C18H22BrO3P
|
1
|
| 1 |
IC50 = 950 nM
|
|
|
|
CP0410783
|
5-chloro-3-[1-diethoxyphosphoryl-2-(4-fluorophenyl)ethyl]-1-phenylindole
Show/Hide
|
C26H26ClFNO3P
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0444317
|
1-bromo-4-[diethoxyphosphoryl(phenyl)methyl]benzene
Show/Hide
|
C17H20BrO3P
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
