Brief Information of the Cell Line and Protein
Cell Line ID: CL000002 , K-562
 Cell Line Info 
Synonyms
K562
K.562
K 562
KO
GM05372
GM05372E
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0004
Protein ID: PT03914 , Nicotinamide N-methyltransferase
 Protein Info 
Gene Name NNMT
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P40261
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000002
 Cell Line Info 
 Protein ID: PT03914
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0564657
 Compound Info 
(2R)-2,4-dimethyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
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C10H13N3O
  1
1
IC50 = 12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578522
 Compound Info 
4-methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
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C9H11N3O
  1
1
IC50 = 23 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0547364
 Compound Info 
4-methyl-6-(methylamino)pyridine-3-carboxamide
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C8H11N3O
  1
1
IC50 = 25 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570183
 Compound Info 
(2R)-2-methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
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C9H11N3O
  1
1
IC50 = 38 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578523
 Compound Info 
4-chloro-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
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C8H8ClN3O
  1
1
IC50 = 79 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568360
 Compound Info 
(2R,3S)-2,3-dimethyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
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C10H13N3O
  1
1
IC50 = 114 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0580248
 Compound Info 
2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
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C8H9N3O
  1
1
IC50 = 142 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS