Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[[[6-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-thiazol-4-yl]methoxy]-2-(trifluoromethyl)pyridin-3-yl]-methylamino]methyl]-3-methylimidazole-4-carboxylic acid
    Show/Hide
 PubChem ID
CID: 168299116
Canonical SMILES
CC(C)c1snc(c1COc1ccc(N(C)Cc2ncc(C(O)=O)n2C)c(n1)C(F)(F)F)-c1c(Cl)cccc1Cl
    Show/Hide
Compound Formula C26H24Cl2F3N5O3S
Compound Structure
Protein Name
 Protein Info 
Bile acid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
>
Nuclear hormone receptor subfamily 1 group H member 4
Uniprot ID
Q96RI1
Gene Name
NR1H4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3190 nM
   TI
   LI
   LO
   TS