Brief Information of the Compound and Protein
Compound Name
6-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-thiazol-4-yl]methoxy]-N-methyl-N-[[3-(2H-tetrazol-5-yl)phenyl]methyl]-2-(trifluoromethyl)pyridin-3-amine
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PubChem ID
CID: 168298037
Canonical SMILES
CC(C)c1snc(c1COc1ccc(N(C)Cc2cccc(c2)-c2nn[nH]n2)c(n1)C(F)(F)F)-c1c(Cl)cccc1Cl
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Compound Formula C28H24Cl2F3N7OS
Compound Structure
Protein Name
Bile acid receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 4
Uniprot ID
Q96RI1
Gene Name
NR1H4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 1120 nM
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