Brief Information of the Compound and Protein
Compound Name
5-[[5-chloro-2-[(3R,5S)-4,4-difluoro-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl]amino]-3-(3-hydroxy-3-methylbutyl)-1-methylbenzimidazol-2-one
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PubChem ID
CID: 135386938
Canonical SMILES
C[C@H]1CN(C[C@@H](C)C1(F)F)c1ncc(Cl)c(Nc2ccc3n(C)c(=O)n(CCC(C)(C)O)c3c2)n1
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Compound Formula C24H31ClF2N6O2
Compound Structure
Protein Name
B-cell lymphoma 6 protein
Protein Classification
Transcription factor
Uniprot ID
P41182
Gene Name
BCL6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000611 OCI-Ly1 Homo sapiens (Human)  1
1
EC50 = 54 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 520 nM