Brief Information of the Compound and Protein
Compound Name
4-(3,6-dichloro-2-fluorobenzoyl)-N-(1-methylpyrazol-4-yl)-1H-pyrrole-2-carboxamide
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PubChem ID
CID: 118959090
Canonical SMILES
Cn1cc(NC(=O)c2cc(c[nH]2)C(=O)c2c(Cl)ccc(Cl)c2F)cn1
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Compound Formula C16H11Cl2FN4O2
Compound Structure
Protein Name
Mitogen-activated protein kinase 7
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase ERK5
Uniprot ID
Q13164
Gene Name
MAPK7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 77 nM
   TI
   LI
   LO
   TS
2
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 141 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 79 nM