Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[2-[6-[(3S)-3-aminopiperidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]ethynyl]-N-[3-chloro-5-(trifluoromethyl)phenyl]-2-methylbenzamide
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 PubChem ID
CID: 162517584
Canonical SMILES
Cc1c(cccc1C(=O)Nc1cc(Cl)cc(c1)C(F)(F)F)C#Cc1cnc2ccc(nn12)N1CCC[C@H](N)C1
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Compound Formula C28H24ClF3N6O
Compound Structure
Protein Name
 Protein Info 
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 17.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22.2 nM
2 IC50 = 2608 nM