Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-chloro-5-(trifluoromethyl)phenyl]-5,18-dimethyl-14-oxo-9-oxa-15,18,23,25,26-pentazatetracyclo[17.5.2.14,8.022,25]heptacosa-1(24),4,6,8(27),19(26),20,22-heptaen-2-yne-6-carboxamide
    Show/Hide
 PubChem ID
CID: 168283365
Canonical SMILES
CN1CCNC(=O)CCCCOc2cc(C#Cc3cnc4ccc1nn34)c(C)c(c2)C(=O)Nc1cc(Cl)cc(c1)C(F)(F)F
    Show/Hide
Compound Formula C31H28ClF3N6O3
Compound Structure
Protein Name
 Protein Info 
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 128.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 32.4 nM