Brief Information of the Compound and Protein
Compound Name
(E)-3-[4-[[2-[3-(1,1-difluoroethyl)-4-fluorophenyl]-6-hydroxy-1-benzothiophen-3-yl]oxy]phenyl]prop-2-enoic acid
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PubChem ID
CID: 168284496
Canonical SMILES
CC(F)(F)c1cc(ccc1F)-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
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Compound Formula C25H17F3O4S
Compound Structure
Protein Name
Estrogen receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001042 HEK293/Gal4 Homo sapiens (Human)  1
1
IC50 = 6.5 nM
   TI
   LI
   LO
   TS
CL000083 MCF-7 Homo sapiens (Human)  1
1
EC50 = 1 nM
   TI
   LI
   LO
   TS