Brief Information of the Compound and Protein
Compound Name
1-[(2R)-3-(4-cyanophenyl)-1-oxo-1-piperidin-1-ylpropan-2-yl]-3-(4-fluorophenyl)urea
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PubChem ID
CID: 168278342
Canonical SMILES
Fc1ccc(NC(=O)N[C@H](Cc2ccc(cc2)C#N)C(=O)N2CCCCC2)cc1
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Compound Formula C22H23FN4O2
Compound Structure
Protein Name
fMet-Leu-Phe receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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N-formyl methionyl peptide receptor
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N-formyl methionyl peptide receptor
Uniprot ID
P21462
Gene Name
FPR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  2
1
EC50 = 18200 nM
   TI
   LI
   LO
   TS
2
IC50 = 30500 nM
   TI
   LI
   LO
   TS