Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl 1-[[4-[5-(3-chloro-4-propan-2-yloxyphenyl)-4,5-dihydro-1,2-oxazol-3-yl]phenyl]methyl]pyrrolidine-3-carboxylate
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 PubChem ID
CID: 166559063
Canonical SMILES
COC(=O)C1CCN(Cc2ccc(cc2)C2=NOC(C2)c2ccc(OC(C)C)c(Cl)c2)C1
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Compound Formula C25H29ClN2O4
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000436 PathHunter CHO-K1 EDG1 beta-arrestin
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 74.4 nM
   TI
   LI
   LO
   TS
CL000435 PathHunter HEK 293 EDG1 Total GPCR Internalization
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 146 nM
   TI
   LI
   LO
   TS