Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl 1-[[4-[4-(4-ethoxyphenyl)triazol-1-yl]phenyl]methyl]azetidine-3-carboxylate
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 PubChem ID
CID: 168294690
Canonical SMILES
CCOc1ccc(cc1)-c1cn(nn1)-c1ccc(CN2CC(C2)C(=O)OC)cc1
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Compound Formula C22H24N4O3
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000436 PathHunter CHO-K1 EDG1 beta-arrestin
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 402 nM
   TI
   LI
   LO
   TS
CL000435 PathHunter HEK 293 EDG1 Total GPCR Internalization
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS