Brief Information of the Compound and Protein
Compound Name
2-amino-5-[7-cyclobutylsulfonyl-2-[(1S)-1-cyclopropylethyl]-1-oxo-3H-isoindol-5-yl]-N-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide
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PubChem ID
CID: 155384020
Canonical SMILES
C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(=O)(=O)C1CCC1)-c1ccn2nc(N)c(C(=O)NC3CC3)c2n1
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Compound Formula C27H30N6O4S
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM