Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-amino-N-cyclopropyl-5-[2-[(1S)-1-cyclopropylethyl]-7-cyclopropylsulfonyl-1-oxo-3H-isoindol-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    Show/Hide
 PubChem ID
CID: 168277245
Canonical SMILES
C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(=O)(=O)C1CC1)-c1ccn2nc(N)c(C(=O)NC3CC3)c2n1
    Show/Hide
Compound Formula C26H28N6O4S
Compound Structure
Protein Name
 Protein Info 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 56 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.7 nM