Brief Information of the Compound and Protein
Compound Name
3-[(1S,3S)-6-chloro-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoquinolin-1-yl]-5-fluorobenzonitrile
    Show/Hide
PubChem ID
CID: 168279356
Canonical SMILES
OC[C@@H]1Cc2cc(Cl)ccc2[C@@H](N1)c1cc(F)cc(c1)C#N
    Show/Hide
Compound Formula C17H14ClFN2O
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily M member 5
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q9NZQ8
Gene Name
TRPM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 251.19 nM
   TI
   LI
   LO
   TS