Brief Information of the Compound and Protein
Compound Name
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-[1-(3-fluorophenyl)ethyl]urea;dihydrochloride
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PubChem ID
CID: 168281745
Canonical SMILES
Cl.Cl.CC(NC(=O)\N=C(/N)NCCCc1nnc(N)s1)c1cccc(F)c1
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Compound Formula C15H22Cl2FN7OS
Compound Structure
Protein Name
Histamine H2 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
P25021
Gene Name
HRH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  2
1
EC50 = 8.128 nM
   TI
   LI
   LO
   TS
2
EC50 = 75.86 nM
   TI
   LI
   LO
   TS