Brief Information of the Compound and Protein
Compound Name
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(3-fluoropyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
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Canonical SMILES
CNc1ncc2cc(-c3ccc(cc3Cl)-c3ncccc3F)c(=O)n(C[C@H]3OC[C@H](N)CO3)c2n1
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Compound Formula C24H22ClFN6O3
Compound Structure
Protein Name
Serine/threonine-protein kinase 26
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase YSK subfamily
Uniprot ID
Q9P289
Gene Name
STK26
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 34000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1600 nM