Brief Information of the Compound and Protein
Compound Name
5-[4-[[1-(3-fluoropropyl)azetidin-3-yl]methyl]phenyl]-6-[3-fluoro-2-(trifluoromethyl)phenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid
    Show/Hide
Canonical SMILES
OC(=O)c1ccc2c(CCCC(c3cccc(F)c3C(F)(F)F)=C2c2ccc(CC3CN(CCCF)C3)cc2)c1
    Show/Hide
Compound Formula C32H30F5NO2
Compound Structure
Protein Name
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7 Homo sapiens (Human)  1
1
IC50 = 0.1 nM
   TI
   LI
   LO
   TS