Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-methylbenzenesulfonamide
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 PubChem ID
CID: 10112384
SID: 15101075
Canonical SMILES
CN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1
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Compound Formula C16H13F6NO3S
Compound Structure
Protein Name
 Protein Info 
Oxysterols receptor LXR-alpha
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
Q13133
Gene Name
NR1H3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3760 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40 nM