Brief Information of the Compound and Protein
Compound Name
US9428500, 43
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PubChem ID
CID: 72195194
Canonical SMILES
CC(C)[Si](C#Cc1ccnc2[nH]c3ccc(cc3c12)-c1ccc(cc1)N1CCN(C)CC1)(C(C)C)C(C)C
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Compound Formula C33H42N4Si
Compound Structure
Protein Name
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 4900 nM
   TI
   LI
   LO
   TS
2
IC50 = 6200 nM
   TI
   LI
   LO
   TS