Brief Information of the Compound and Protein
Compound Name
N-(quinolin-8-ylcarbamothioyl)-1,3-benzodioxole-5-carboxamide
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PubChem ID
CID: 168277422
Canonical SMILES
O=C(NC(=S)Nc1cccc2cccnc12)c1ccc2OCOc2c1
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Compound Formula C18H13N3O3S
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  5
1
EC50 = 8310 nM
   TI
   LI
   LO
   TS
2
EC50 = 9140 nM
   TI
   LI
   LO
   TS
3
EC50 = 9440 nM
   TI
   LI
   LO
   TS
4
IC50 = 18 nM
   TI
   LI
   LO
   TS
5
IC50 = 30 nM
   TI
   LI
   LO
   TS