Brief Information of the Compound and Protein
Compound Name
5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinolin-1-one
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PubChem ID
CID: 3064778
SID: 14898703
Canonical SMILES
O=c1[nH]ccc2c(cccc12)S(=O)(=O)N1CCCNCC1
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Compound Formula C14H17N3O3S
Compound Structure
Protein Name
Rho-associated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
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AGC protein kinase ROCK subfamily
Uniprot ID
O75116
Gene Name
ROCK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 194 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 575.44 nM
2 IC50 = 600 nM