Brief Information of the Compound and Protein
Compound Name
2-[2-[[4-[(8-chloro-7-methylquinolin-2-yl)amino]cyclohexyl]methylamino]pyrimidin-5-yl]-2,2-difluoro-N-(oxetan-3-yl)acetamide
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Canonical SMILES
Cc1ccc2ccc(N[C@H]3CC[C@H](CNc4ncc(cn4)C(F)(F)C(=O)NC4COC4)CC3)nc2c1Cl
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Compound Formula C26H29ClF2N6O2
Compound Structure
Protein Name
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000175 G-401 Homo sapiens (Human)  1
1
IC50 < 10 nM
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