Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(quinolin-8-ylcarbamothioyl)adamantane-1-carboxamide
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 PubChem ID
CID: 168285838
Canonical SMILES
O=C(NC(=S)Nc1cccc2cccnc12)C12CC3CC(CC(C3)C1)C2
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Compound Formula C21H23N3OS
Compound Structure
Protein Name
 Protein Info 
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 2192 nM
   TI
   LI
   LO
   TS
2
EC50 = 6084 nM
   TI
   LI
   LO
   TS
3
EC50 = 6617 nM
   TI
   LI
   LO
   TS
4
IC50 = 68 nM
   TI
   LI
   LO
   TS
5
IC50 = 73 nM
   TI
   LI
   LO
   TS