Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-2-propan-2-yl-3,4-dihydro-2,7-naphthyridin-1-one
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 PubChem ID
CID: 168287504
Canonical SMILES
CC(C)N1CCc2c(cnc(N)c2C1=O)-c1cnn(c1)C1CCNCC1
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Compound Formula C19H26N6O
Compound Structure
Protein Name
 Protein Info 
Activin receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR1
Uniprot ID
Q04771
Gene Name
ACVR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 410 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 72 nM