Brief Information of the Compound and Protein
Compound Name
2-chloro-4-[(4-hydroxyphenyl)methylamino]-5-phenyl-5H-thieno[2,3-d]pyrimidin-6-one
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PubChem ID
CID: 163410274
Canonical SMILES
Oc1ccc(CNc2nc(Cl)nc3SC(=O)C(c23)c2ccccc2)cc1
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Compound Formula C19H14ClN3O2S
Compound Structure
Protein Name
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  2
1
EC50 = 40 nM
   TI
   LI
   LO
   TS
2
EC50 = 48 nM
   TI
   LI
   LO
   TS