Brief Information of the Compound and Protein
Compound Name
4-[[[2-chloro-5-(2-methylpropyl)thieno[2,3-d]pyrimidin-4-yl]amino]methyl]phenol
    Show/Hide
PubChem ID
CID: 166419786
Canonical SMILES
CC(C)Cc1csc2nc(Cl)nc(NCc3ccc(O)cc3)c12
    Show/Hide
Compound Formula C17H18ClN3OS
Compound Structure
Protein Name
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  2
1
EC50 = 31 nM
   TI
   LI
   LO
   TS
2
EC50 = 240 nM
   TI
   LI
   LO
   TS