Brief Information of the Compound and Protein
Compound Name
4-[[(2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino]methyl]phenol
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PubChem ID
CID: 154872580
Canonical SMILES
Oc1ccc(CNc2nc(Cl)nc3scc(-c4ccccc4)c23)cc1
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Compound Formula C19H14ClN3OS
Compound Structure
Protein Name
Estrogen receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  2
1
EC50 = 11 nM
   TI
   LI
   LO
   TS
2
EC50 = 48 nM
   TI
   LI
   LO
   TS
CL000083 MCF-7 Homo sapiens (Human)  1
1
IC50 = 65 nM
   TI
   LI
   LO
   TS