Brief Information of the Compound and Protein
Compound Name
3-amino-N-cyclohexyl-6-[4-[(dimethylamino)methyl]phenyl]pyrazine-2-carboxamide
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PubChem ID
CID: 168278781
Canonical SMILES
CN(C)Cc1ccc(cc1)-c1cnc(N)c(n1)C(=O)NC1CCCCC1
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Compound Formula C20H27N5O
Compound Structure
Protein Name
Activin receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR1
Uniprot ID
Q04771
Gene Name
ACVR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM