Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-[4-[3-(4-aminophenyl)-7-hydroxy-2-oxo-1H-quinoline-4-carbonyl]phenoxy]ethyl]-6-oxo-2,5-dihydropyridine-3-carboxylic acid
    Show/Hide
 PubChem ID
CID: 168277913
Canonical SMILES
Nc1ccc(cc1)-c1c(C(=O)c2ccc(OCCN3CC(=CCC3=O)C(O)=O)cc2)c2ccc(O)cc2[nH]c1=O
    Show/Hide
Compound Formula C30H25N3O7
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 > 100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 37 nM
2 Ka = 0.04 nM