Brief Information of the Compound and Protein
Compound Name
5-[[5-methyl-2-[[6-(4-methylpiperazin-1-yl)pyridin-3-yl]amino]pyrimidin-4-yl]amino]-3H-1,3-benzoxazol-2-one
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PubChem ID
CID: 66659601
Canonical SMILES
CN1CCN(CC1)c1ccc(Nc2ncc(C)c(Nc3ccc4oc(=O)[nH]c4c3)n2)cn1
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Compound Formula C22H24N8O2
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000251 Cheptage Homo sapiens (Human)  1
1
IC50 = 84 nM
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