Brief Information of the Compound and Protein
Compound Name
5-[[2-[4-fluoro-3-(trifluoromethyl)anilino]-5-methylpyrimidin-4-yl]amino]-3H-1,3-benzoxazol-2-one
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PubChem ID
CID: 66660178
Canonical SMILES
Cc1cnc(Nc2ccc(F)c(c2)C(F)(F)F)nc1Nc1ccc2oc(=O)[nH]c2c1
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Compound Formula C19H13F4N5O2
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000251 Cheptage Homo sapiens (Human)  1
1
IC50 = 503 nM
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