Brief Information of the Compound and Protein
Compound Name
5-[[2-(3-methoxy-5-methylanilino)-5-methylpyrimidin-4-yl]amino]-3H-1,3-benzoxazol-2-one
    Show/Hide
PubChem ID
CID: 66659646
Canonical SMILES
COc1cc(C)cc(Nc2ncc(C)c(Nc3ccc4oc(=O)[nH]c4c3)n2)c1
    Show/Hide
Compound Formula C20H19N5O3
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000251 Cheptage Homo sapiens (Human)  1
1
IC50 = 354 nM
   TI
   LI
   LO
   TS