Brief Information of the Compound and Protein
Compound Name
4-[2-[(2-fluorophenyl)methylamino]ethyl]-2,5-dimethoxybenzonitrile
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PubChem ID
CID: 168290300
Canonical SMILES
COc1cc(C#N)c(OC)cc1CCNCc1ccccc1F
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Compound Formula C18H19FN2O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28223
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  4
1
EC50 = 53.2 nM
   TI
   LI
   LO
   TS
2
EC50 = 168 nM
   TI
   LI
   LO
   TS
3
EC50 = 661 nM
   TI
   LI
   LO
   TS
4
EC50 = 1126 nM
   TI
   LI
   LO
   TS