Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea
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 PubChem ID
CID: 9910393
SID: 14928476
Canonical SMILES
CC(C)(O)c1coc(c1)S(=O)(=O)NC(=O)Nc1c2CCCc2cc2CCCc12
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Compound Formula C20H24N2O5S
Compound Structure
Protein Name
 Protein Info 
NACHT, LRR and PYD domains-containing protein 3
Protein Classification
Unclassified protein
Uniprot ID
Q8R4B8
Gene Name
NLRP3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000188 J774A1
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 21.88 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7.5 nM
2 IC50 = 40 nM