Brief Information of the Compound and Protein
Compound Name
[4-amino-2-[4-(4-methylpiperazin-1-yl)anilino]-1,3-thiazol-5-yl]-[2-fluoro-6-(trifluoromethyl)phenyl]methanone
    Show/Hide
PubChem ID
CID: 18521917
Canonical SMILES
CN1CCN(CC1)c1ccc(Nc2nc(N)c(s2)C(=O)c2c(F)cccc2C(F)(F)F)cc1
    Show/Hide
Compound Formula C22H21F4N5OS
Compound Structure
Protein Name
Cyclin-dependent kinase 11A
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase CDK family
>
CMGC protein kinase PITSLRE subfamily
Uniprot ID
Q9UQ88
Gene Name
CDK11A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 900 nM
   TI
   LI
   LO
   TS