Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 18
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 PubChem ID
CID: 11249084
SID: 16333778
Canonical SMILES
CCc1cccc(CC)c1NC(=O)N1Cc2n[nH]c(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1
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Compound Formula C28H35N7O2
Compound Structure
Protein Name
 Protein Info 
LIM domain kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LISK family
>
TKL protein kinase LIMK subfamily
Uniprot ID
P53667
Gene Name
LIMK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 407.38 nM
2 IC50 = 575.44 nM