Brief Information of the Compound and Protein
Compound Name
7-anilino-3-phenyl-1H-pyrazolo[3,4-c]pyridine-5-carbonitrile
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PubChem ID
CID: 168272324
Canonical SMILES
N#Cc1cc2c(n[nH]c2c(Nc2ccccc2)n1)-c1ccccc1
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Compound Formula C19H13N5
Compound Structure
Protein Name
Adenosine receptor A1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Nucleotide-like receptor (family A GPCR)
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Adenosine receptor
Uniprot ID
P30542
Gene Name
ADORA1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 13.49 nM
   TI
   LI
   LO
   TS
2
Ki = 213.8 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Kd = 61.66 nM
   TI
   LI
   LO
   TS