Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-benzyl-N-butyl-4-(phenylsulfamoyl)benzamide
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 PubChem ID
CID: 137796294
Canonical SMILES
CCCCN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1
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Compound Formula C24H26N2O3S
Compound Structure
Protein Name
 Protein Info 
LIM domain kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LISK family
>
TKL protein kinase LIMK subfamily
Uniprot ID
P53667
Gene Name
LIMK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 238 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 229.09 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
Kd = 682 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 83.8 nM
2 IC50 = 194.98 nM
3 IC50 = 199.53 nM
4 IC50 = 824 nM
5 Kd = 120 nM