Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BGJ398
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 PubChem ID
CID: 53235510
SID: 124359248
Canonical SMILES
CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)cc1
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Compound Formula C26H31Cl2N7O3
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 2.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 0.5 nM
2 IC50 = 0.66 nM
3 IC50 = 1 nM
4 IC50 = 1.8 nM
5 IC50 = 44.4 nM
6 IC50 = 352 nM
7 IC50 = 505.9 nM