Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-propan-2-yl-5-[2-[1-(thiophen-2-ylmethyl)piperidin-4-yl]-1H-pyrrolo[2,3-b]pyridin-4-yl]pyridin-2-one
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 PubChem ID
CID: 168288694
Canonical SMILES
CC(C)n1cc(ccc1=O)-c1ccnc2[nH]c(cc12)C1CCN(Cc2cccs2)CC1
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Compound Formula C25H28N4OS
Compound Structure
Protein Name
 Protein Info 
Cyclin-dependent kinase 9
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase CDK family
>
CMGC protein kinase CDK9 subfamily
Uniprot ID
P50750
Gene Name
CDK9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14 nM