Brief Information of the Compound and Protein
Compound Name
US9073922, 18
    Show/Hide
PubChem ID
CID: 90412502
Canonical SMILES
COc1cc(F)ccc1-c1ccnc2[nH]c(cc12)C1CCNCC1
    Show/Hide
Compound Formula C19H20FN3O
Compound Structure
Protein Name
Cyclin-dependent kinase 9
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase CDK family
>
CMGC protein kinase CDK9 subfamily
Uniprot ID
P50750
Gene Name
CDK9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7 Homo sapiens (Human)  1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 3 nM
2 IC50 = 6 nM
3 IC50 = 19 nM