Brief Information of the Compound and Protein
Compound Name
(E)-N-hydroxy-3-[4-[4-(3,4,5-trimethoxybenzoyl)-1,3-thiazol-2-yl]phenyl]prop-2-enamide
    Show/Hide
PubChem ID
CID: 168289455
Canonical SMILES
COc1cc(cc(OC)c1OC)C(=O)c1csc(n1)-c1ccc(\C=C\C(=O)NO)cc1
    Show/Hide
Compound Formula C22H20N2O6S
Compound Structure
Protein Name
Histone deacetylase 8
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class I
Uniprot ID
Q9BY41
Gene Name
HDAC8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 2710 nM
   TI
   LI
   LO
   TS