Brief Information of the Compound and Protein
| Compound Name |
pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Histone deacetylase 8
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Protein Classification |
Epigenetic regulator
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Eraser
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Histone deacetylase
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HDAC class I
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| Uniprot ID | Gene Name | HDAC8 |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000013 | Sf9 | Spodoptera frugiperda (Fall armyworm) | 1 |
| 1 |
IC50 = 17840 nM
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TI
LI
LO
TS
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Biochemical Assays
| 1 | IC50 = 181 nM | ||
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| 2 | IC50 = 1440 nM | ||
| 3 | IC50 = 3200 nM | ||
| 4 | IC50 = 9880 nM | ||
| 5 | IC50 = 9884 nM | ||
| 6 | IC50 = 14120 nM | ||
| 7 | IC50 = 44900 nM | ||
| 8 | IC50 = 63400 nM | ||
| 9 | IC50 > 10000 nM | ||
| 10 | IC50 > 40000 nM | ||