Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R)-2-[2-[1-[(1R)-1-(2,6-dichloro-3-cyclopropylphenyl)ethyl]imidazo[4,5-c]pyridin-6-yl]phenyl]propanoic acid
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Canonical SMILES
C[C@@H](C(O)=O)c1ccccc1-c1cc2n(cnc2cn1)[C@H](C)c1c(Cl)ccc(C2CC2)c1Cl
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Compound Formula C26H23Cl2N3O2
Compound Structure
Protein Name
 Protein Info 
Glucagon-like peptide 1 receptor
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Glucagon-like receptor
>
Glucagon-like peptide receptor
Uniprot ID
P43220
Gene Name
GLP1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 12 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 0.085 nM
   TI
   LI
   LO
   TS
2
EC50 = 7 nM
   TI
   LI
   LO
   TS
3
EC50 = 270 nM
   TI
   LI
   LO
   TS
4
EC50 = 1800 nM
   TI
   LI
   LO
   TS
CL000230 INS-1 832/13
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
EC50 = 7 nM
   TI
   LI
   LO
   TS