Brief Information of the Compound and Protein
Compound Name
N-[[4-(cyclopropylsulfonylamino)-2-(trifluoromethyl)phenyl]methyl]-1-[(3-fluorophenyl)methyl]indole-5-carboxamide
    Show/Hide
Canonical SMILES
Fc1cccc(Cn2ccc3cc(ccc23)C(=O)NCc2ccc(NS(=O)(=O)C3CC3)cc2C(F)(F)F)c1
    Show/Hide
Compound Formula C27H23F4N3O3S
Compound Structure
Protein Name
Peroxisome proliferator-activated receptor gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group C
>
Nuclear hormone receptor subfamily 1 group C member 3
Uniprot ID
P37231
Gene Name
PPARG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 220 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 180 nM