Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-[2-[(7-ethoxy-6-fluoroquinazolin-4-yl)amino]ethyl]phenyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]urea
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 PubChem ID
CID: 166632692
Canonical SMILES
CCOc1cc2ncnc(NCCc3ccc(NC(=O)Nc4cc(ccc4OC)C(F)(F)F)cc3)c2cc1F
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Compound Formula C27H25F4N5O3
Compound Structure
Protein Name
 Protein Info 
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 21.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 21.4 nM