Brief Information of the Compound and Protein
Compound Name
N-(4-tert-butylphenyl)-2-[4-[[4-[(5-methyl-1H-pyrazol-3-yl)amino]-6-morpholin-4-ylpyrimidin-2-yl]amino]phenyl]acetamide
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PubChem ID
CID: 166627493
Canonical SMILES
Cc1cc(Nc2cc(nc(Nc3ccc(CC(=O)Nc4ccc(cc4)C(C)(C)C)cc3)n2)N2CCOCC2)[nH]n1
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Compound Formula C30H36N8O2
Compound Structure
Protein Name
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Ret family
Uniprot ID
P07949
Gene Name
RET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 140.65 nM
   TI
   LI
   LO
   TS