Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-[[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]amino]phenyl]-N-[(3-fluorophenyl)methyl]acetamide
    Show/Hide
 PubChem ID
CID: 162395610
Canonical SMILES
CN1CCN(CC1)c1cc(Nc2cc(n[nH]2)C2CC2)nc(Nc2ccc(CC(=O)NCc3cccc(F)c3)cc2)n1
    Show/Hide
Compound Formula C30H34FN9O
Compound Structure
Protein Name
 Protein Info 
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Ret family
Uniprot ID
P07949
Gene Name
RET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 10.52 nM
   TI
   LI
   LO
   TS