Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-[[4-[(5-tert-butyl-1H-pyrazol-3-yl)amino]-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]amino]phenyl]-N-[(3-fluorophenyl)methyl]acetamide
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 PubChem ID
CID: 166627573
Canonical SMILES
CN1CCN(CC1)c1cc(Nc2cc(n[nH]2)C(C)(C)C)nc(Nc2ccc(CC(=O)NCc3cccc(F)c3)cc2)n1
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Compound Formula C31H38FN9O
Compound Structure
Protein Name
 Protein Info 
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Ret family
Uniprot ID
P07949
Gene Name
RET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 252.25 nM
   TI
   LI
   LO
   TS